[
{":id":"row-zpx5.b2z3~ke8x",":version":"rv-96yx~58sb.7v87",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A02","tree_category":"Musculoskeletal System","mesh_heading":"Myotendinous Junction","scope_note":"A specialized interface between muscle and tendon through which most contractile force is transmitted. It consists of elaborate surface folding called interdigitations involving EXTRACELLULAR MATRIX and terminal SARCOMERES."},
{":id":"row-hjec.azt5.imib",":version":"rv-e8kb_qt84.cded",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A06","tree_category":"Endocrine System","mesh_heading":"Hypothalamic-Pituitary-Gonadal Axis","scope_note":"A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS, the PITUITARY GLAND and the GONADS. It plays a central role in endocrine regulation of gonadal function including release of hormones: GNRH; LUTEINIZING HORMONE; FOLLICLE-STIMULATING HORMONE and TESTOSTERONE."},
{":id":"row-g7wg~a8h7~nyjv",":version":"rv-3zcg-b6pe.s4u2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A08","tree_category":"Nervous System","mesh_heading":"Hypothalamic-Pituitary-Gonadal Axis","scope_note":"A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS, the PITUITARY GLAND and the GONADS. It plays a central role in endocrine regulation of gonadal function including release of hormones: GNRH; LUTEINIZING HORMONE; FOLLICLE-STIMULATING HORMONE and TESTOSTERONE."},
{":id":"row-s42y-83er~f3it",":version":"rv-rbzu.u2aw~hrb7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A08","tree_category":"Nervous System","mesh_heading":"Medium Spiny Neurons","scope_note":"Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE."},
{":id":"row-tbuu.27xf~y5jq",":version":"rv-3n49-kgh5-fxkd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A08","tree_category":"Nervous System","mesh_heading":"Schaffer Collaterals","scope_note":"The main axon connection from the CA3 PYRAMIDAL CELL AREA to the CA1 PYRAMIDAL CELL AREA in the HIPPOCAMPUS. Schaffer collaterals are important in memory, learning and activity-related NEURONAL PLASTICITY."},
{":id":"row-r8j6_8bni~6ben",":version":"rv-4f96_u4yj~mke5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A09","tree_category":"Sense Organs","mesh_heading":"Schlemm's Canal","scope_note":"A circular vascular-like structure in the anterior chamber of the eye bounded anterolaterally by the internal scleral sulcus and posteriorly by the trabecular meshwork. It is a part of a pathway where the AQUEOUS HUMOR from the ANTERIOR CHAMBER of the eye passes through the TRABECULAR MESHWORK, drains into the lumen of Schlemm’s canal, and subsequently returns to blood circulation into the veins of the SCLERA."},
{":id":"row-mwp6-nmsh~ct4s",":version":"rv-3iza-rmzs~4kyj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A10","tree_category":"Tissues","mesh_heading":"M Cells","scope_note":"A distinct lineage of epithelial cells, present in MUCOSAL TISSUE, that is responsible for the immune sensing and capture of luminal bacteria and other microparticles. They deliver these microparticles, via TRANSCYTOSIS, to lymphoid tissue for efficient mucosal as well as systemic immune responses. Inflammation-induced M cells arising in response to inflammatory conditions may provide microbial access to tissues without normal M cell-associated immune surveillance tissue."},
{":id":"row-9hi8-rfdx_budz",":version":"rv-f6ab-ia3z.vijx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A10","tree_category":"Tissues","mesh_heading":"Microphysiological Systems","scope_note":"Devices designed to recapitulate tissue or organ-level physiology and architect by combining MICROFLUIDICS; MICROFABRICATION; and 3D CELL CULTURE. Microphysiological systems mimic interconnections important in physiological or pathophysiological states of organ(s) and are often used for instance in HIGH THROUGHPUT SCREENING of drugs and factors important in disease modeling."},
{":id":"row-4aae-9gnh-k958",":version":"rv-yt9v~cqkn~jm3x",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A11","tree_category":"Cells","mesh_heading":"Limbal Stem Cells","scope_note":"Adult somatic stem cells found in the basal epithelial layer of the LIMBUS CORNEAE."},
{":id":"row-wa3u_5dq4_qxnj",":version":"rv-3kx6-um55.e5zw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A11","tree_category":"Cells","mesh_heading":"M Cells","scope_note":"A distinct lineage of epithelial cells, present in MUCOSAL TISSUE, that is responsible for the immune sensing and capture of luminal bacteria and other microparticles. They deliver these microparticles, via TRANSCYTOSIS, to lymphoid tissue for efficient mucosal as well as systemic immune responses. Inflammation-induced M cells arising in response to inflammatory conditions may provide microbial access to tissues without normal M cell-associated immune surveillance tissue."},
{":id":"row-izmk-nkz4-fibi",":version":"rv-etrh_b5md_t2d3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A11","tree_category":"Cells","mesh_heading":"MDA-MB-231 Cells","scope_note":"A human breast cancer cell line that was derived in 1973 from the MALIGNANT PLEURAL EFFUSION of a patient with stage III BREAST CARCINOMA and was characterized as being of breast cancer origin."},
{":id":"row-6af9_r6jw_jsz2",":version":"rv-dvh5~uzk4.5xiw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A11","tree_category":"Cells","mesh_heading":"Medium Spiny Neurons","scope_note":"Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE."},
{":id":"row-fmwh_atj8_cpu9",":version":"rv-nmie_gxmb~y6j3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"A11","tree_category":"Cells","mesh_heading":"Schaffer Collaterals","scope_note":"The main axon connection from the CA3 PYRAMIDAL CELL AREA to the CA1 PYRAMIDAL CELL AREA in the HIPPOCAMPUS. Schaffer collaterals are important in memory, learning and activity-related NEURONAL PLASTICITY."},
{":id":"row-bwbq.7wg5_jwrm",":version":"rv-sing~2kcw~iejy",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B01","tree_category":"Eukaryota","mesh_heading":"Lysimachia","scope_note":"A plant genus of the family  PRIMULACEAE. Lysimachia are used for  herbal medicinal purposes. Common name loosestrife refers to members of Lysimachia (e.g., yellow loosestrife) and another plant family Lythrum (purple loosestrife)."},
{":id":"row-zykk.tsfd~2f8j",":version":"rv-ri4v~hys2_sjdj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B01","tree_category":"Eukaryota","mesh_heading":"Schinus","scope_note":"A plant genus of the family ANACARDIACEAE."},
{":id":"row-8fbh~kccw_k432",":version":"rv-6euy~wwvi~jsiq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B01","tree_category":"Eukaryota","mesh_heading":"Sigesbeckia","scope_note":"A plant genus of the family ASTERACEAE. It has been used in traditional herbal medicine and commonly referred to as St. Paul's wort. It produces an unpleasant smell and is sometimes referred to as pig pungent weed."},
{":id":"row-zkdj.4f8j.tn9s",":version":"rv-k4gb_wbxv.xx6m",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B01","tree_category":"Eukaryota","mesh_heading":"Sophora flavescens","scope_note":"A Sophora species commonly used as medicinal herb and is main source of quinolizidine alkaloid MATRINES. It is a perennial with yellow flowers."},
{":id":"row-d8cw_3qm7-jftj",":version":"rv-5efj~nbpm_zv68",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B01","tree_category":"Eukaryota","mesh_heading":"Sophora japonica","scope_note":"A member of the family FABACEAE, native to the FAR EAST and used in traditional medicine. Sophora japonica yellow flower bud and dried fruit extracts  are rich in FLAVONOIDS, e.g., SOPHORICOSIDE and RUTIN."},
{":id":"row-hucu.ku7g-dgf6",":version":"rv-mccw.hpnw-t6mv",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B03","tree_category":"Bacteria","mesh_heading":"Lacticaseibacillus","scope_note":"A genus of gram-positive, non-motile, homofermentative, oxidase negative, rod-shaped bacteria occurring widely in nature. Its species previously were referred to as Lactobacillus casei group. The genus harbors several species that are used as starter cultures in dairy fermentations and as probiotics."},
{":id":"row-9yzc_q4b4.9ccm",":version":"rv-g9fc-4ebp~9vpr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"B04","tree_category":"Viruses","mesh_heading":"Human Papillomavirus Viruses","scope_note":"A large group of viruses that cause HUMAN PAPILLOMAVIRUS INFECTION, e.g., GENITAL WARTS and cancer of the CERVIX; VAGINA; VULVA; ANUS; or OROPHARYNX. Most common clinically important human papilloma viruses are taxonomically members of ALPHAPAPILLOMAVIRUS and GAMMAPAPILLOMAVIRUS."},
{":id":"row-pbup_9j5g~e6wf",":version":"rv-pjsi-ie67~snei",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C01","tree_category":"Infections","mesh_heading":"Allergic Fungal Sinusitis","scope_note":"Fungal infection in the PARANASAL SINUSES characterized by common allergy respiratory symptoms, recurrent NASAL POLYPS and/or ASTHMA with buildup of allergic MUCIN."},
{":id":"row-bnkm.efca~zxh7",":version":"rv-w7ti-hfu3-wp2g",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C01","tree_category":"Infections","mesh_heading":"Breakthrough Infections","scope_note":"Infections by the same infectious agent (e.g., virus, fungus) occurring during exposure to prophylaxis, vaccine and treatment."},
{":id":"row-5v9p_4w83-pxqh",":version":"rv-vxig~fqh7~34tt",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C01","tree_category":"Infections","mesh_heading":"Post-Acute COVID-19 Syndrome","scope_note":"Post acute stage of COVID-19 virus infection. Persistent symptoms may include FATIGUE; DYSPNEA; and MEMORY LOSS."},
{":id":"row-uyyy-amwa~agnr",":version":"rv-tbuk~dcrk-jjr9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C01","tree_category":"Infections","mesh_heading":"Tuberculosis, Extrapulmonary","scope_note":"MYCOBACTERIUM infections of organs other than the lung."},
{":id":"row-npi8~ask5.sf2b",":version":"rv-5rnb~82bx~k2ck",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C04","tree_category":"Neoplasms","mesh_heading":"Non-Muscle Invasive Bladder Neoplasms","scope_note":"A urothelial carcinoma found in the tissue that lines the inner surface of the bladder. The bladder muscle is not involved."},
{":id":"row-8bqf-wrhk_cwqt",":version":"rv-9tza-7fyw~zct3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C05","tree_category":"Musculoskeletal Diseases","mesh_heading":"Dropped Head Syndrome","scope_note":"Condition characterized by sagging of the head due to severe NECK MUSCLES weakness in the back of the neck. It may result in severe cervical KYPHOSIS called chin-on-chest deformity. Dropped head syndrome is most often associated with other diseases, e.g., PARKINSON'S DISEASE; STROKES; HEAD AND NECK CANCER; and ANKYLOSING SPONDYLITIS."},
{":id":"row-gtyu-af8m~4gip",":version":"rv-6sy3_rmia.pady",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C06","tree_category":"Digestive System Diseases","mesh_heading":"Idiopathic Noncirrhotic Portal Hypertension","scope_note":"Portal hypertension without known risk factors for hypertension, e.g., HEPATIC CIRRHOSIS and SCHISTOSOMIASIS. Idiopathic Noncirrhotic Portal Hypertension is most often associated with pathology in the PORTAL SYSTEM vasculature."},
{":id":"row-zc9f~nsdz.8wqe",":version":"rv-c7m4.phrk.76av",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C06","tree_category":"Digestive System Diseases","mesh_heading":"Low Anterior Resection Syndrome","scope_note":"Postoperative complication after removal of the RECTUM (low anterior resection surgery or resection surgery to the lower part of the COLON). It includes disordered rectum function, e.g., frequent BOWEL MOVEMENT; FECAL INCONTINENCE; and CONSTIPATION."},
{":id":"row-haay-23qc~x22w",":version":"rv-r5cg.dht8.w46x",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C06","tree_category":"Digestive System Diseases","mesh_heading":"Pancreas Divisum","scope_note":"Anatomic variants in PANCREATIC DUCTS characterized by failure of fusion of the ventral and dorsal endodermal buds. Pancreas divisum results in inadequate or no communication between dorsal and ventral ducts. While most cases are asymptomatic, it may be associated with recurrent PANCREATITIS."},
{":id":"row-pp9s-kmbn_rdsc",":version":"rv-yusa~a8yv-xukj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C06","tree_category":"Digestive System Diseases","mesh_heading":"Sinistral Portal Hypertension","scope_note":"Portal hypertension of the SPLENIC VEIN due to occlusion caused by pancreatic pathology such as PANCREATIC PSEUDOCYST and PANCRATIC CANCER. Sinistral portal hypertension is associated with GASTRIC VARICES and acute HEMATEMESIS."},
{":id":"row-jk5n.bv6u~jpda",":version":"rv-pcxk_dx2g~f864",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C07","tree_category":"Stomatognathic Diseases","mesh_heading":"Dental Enamel Hypomineralization","scope_note":"Reduced mineralization disorder of the DENTAL ENAMEL during development resulting in qualitative defects, e.g., discolored or chalky (soft) enamel."},
{":id":"row-maba.hsqk.6hb3",":version":"rv-s9iz_gz9u-6cfc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C07","tree_category":"Stomatognathic Diseases","mesh_heading":"Developmental Defects of Enamel","scope_note":"Defects in normal AMELOGENESIS caused by any local, systemic, environmental, or genetic factors. Enamel defects resulting from demineralization of normally developed DENTAL ENAMEL is referred to as TOOTH DEMINERALIZATION."},
{":id":"row-j99a~zf8f.24nn",":version":"rv-qvgj_955t-hq6r",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C07","tree_category":"Stomatognathic Diseases","mesh_heading":"Molar Hypomineralization","scope_note":"A type of developmental disturbance of AMELOGENESIS involving MOLARS of any type (obligatory) plus other teeth sometimes. It is characterized by demarcated enamel opacities with unknown systemic causation (idiopathic)."},
{":id":"row-ceh4-5ike_cirk",":version":"rv-ji2z-gfyt_fhw5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C08","tree_category":"Respiratory Tract Diseases","mesh_heading":"Allergic Fungal Sinusitis","scope_note":"Fungal infection in the PARANASAL SINUSES characterized by common allergy respiratory symptoms, recurrent NASAL POLYPS and/or ASTHMA with buildup of allergic MUCIN."},
{":id":"row-egtx_hrft.i7a9",":version":"rv-w8e4~vqks.6c46",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C08","tree_category":"Respiratory Tract Diseases","mesh_heading":"Bronchiolitis Obliterans Syndrome","scope_note":"Bronchiolitis obliterans complication from allogenic HEMATOPOIETIC STEM CELL TRANSPLANTATION and LUNG TRANSPLANTATION."},
{":id":"row-m3qp~uv3v-fi3z",":version":"rv-ijtm.qtuh~nfhm",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C08","tree_category":"Respiratory Tract Diseases","mesh_heading":"Dust Mite Allergy","scope_note":"Allergic rhinitis due to HOUSE DUST MITE ALLERGENS (e.g., Der p 1 of HOUSE DUST MITES) that is triggered by the immune system."},
{":id":"row-h5mz-3sd2_dnaa",":version":"rv-ums6_53hm.mrjj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C08","tree_category":"Respiratory Tract Diseases","mesh_heading":"Organizing Pneumonia","scope_note":"Any obstructive lung disease characterized by consolidated formation of GRANULATION TISSUE polyps within ALVEOLAR DUCTS AND ALVEOLI. It is classified as either primary (cryptogenic organizing pneumonia) or secondary organizing pneumonia. Secondary organizing pneumonia after transplantation is called bronchiolitis obliterans syndrome."},
{":id":"row-vqte.q6ud_idci",":version":"rv-3n94_ky9k-ymva",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C08","tree_category":"Respiratory Tract Diseases","mesh_heading":"Platypnea Orthodeoxia Syndrome","scope_note":"Orthostatic dyspnea and fall of oxygen blood saturation when standing up which regress by assuming lying position."},
{":id":"row-mxwv_rtgv-48g7",":version":"rv-ykky_r4c3-akjh",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C08","tree_category":"Respiratory Tract Diseases","mesh_heading":"Post-Acute COVID-19 Syndrome","scope_note":"Post acute stage of COVID-19 virus infection. Persistent symptoms may include FATIGUE; DYSPNEA; and MEMORY LOSS."},
{":id":"row-yvdj.hzqh-g2sk",":version":"rv-hc5j.9ced.umuq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C09","tree_category":"Otorhinolaryngologic Diseases","mesh_heading":"Allergic Fungal Sinusitis","scope_note":"Fungal infection in the PARANASAL SINUSES characterized by common allergy respiratory symptoms, recurrent NASAL POLYPS and/or ASTHMA with buildup of allergic MUCIN."},
{":id":"row-4szu~cwzf-6yfk",":version":"rv-gms5_py7d_iv2r",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C09","tree_category":"Otorhinolaryngologic Diseases","mesh_heading":"Dust Mite Allergy","scope_note":"Allergic rhinitis due to HOUSE DUST MITE ALLERGENS (e.g., Der p 1 of HOUSE DUST MITES) that is triggered by the immune system."},
{":id":"row-zsbs.xqat.39dh",":version":"rv-4mgi~4ix3-4yf2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C09","tree_category":"Otorhinolaryngologic Diseases","mesh_heading":"Tympanosclerosis","scope_note":"Calcification of the TYMPANIC MEMBRANE and MIDDLE EAR most often associated with chronic OTITIS MEDIA."},
{":id":"row-vjr3~an38-qvir",":version":"rv-bzzy_25r7_5j83",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C10","tree_category":"Nervous System Diseases","mesh_heading":"Congenital Cranial Dysinnervation Disorders","scope_note":"Congenital neurodevelopmental diseases characterized by abnormal eye, eyelid, and facial movements. Congenital cranial dysinnervation disorders (CCDDs) are caused by abnormal innervation of CRANIAL NERVES (e.g., CNs III, IV and VI) resulting in aplasia or hypoplasia of the ocular and facial musculature involved in EYE MOVEMENTS."},
{":id":"row-vuav-8zd3_nxd6",":version":"rv-krcv-bx54~2xd7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C10","tree_category":"Nervous System Diseases","mesh_heading":"Dropped Head Syndrome","scope_note":"Condition characterized by sagging of the head due to severe NECK MUSCLES weakness in the back of the neck. It may result in severe cervical KYPHOSIS called chin-on-chest deformity. Dropped head syndrome is most often associated with other diseases, e.g., PARKINSON'S DISEASE; STROKES; HEAD AND NECK CANCER; and ANKYLOSING SPONDYLITIS."},
{":id":"row-aj8q-brcs_72fu",":version":"rv-eaba~wusc.tavc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C10","tree_category":"Nervous System Diseases","mesh_heading":"Focal Cortical Dysplasia","scope_note":"Abnormal, non-neoplastic cell proliferation of the CEREBRAL CORTEX confined to an area in any lobe. Focal cortical dysplasia in the temporal lobe is associated with TEMPORAL LOBE EPILEPSY."},
{":id":"row-c3x9.wgkc.rd6k",":version":"rv-dpxe~dmim.mvtx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C10","tree_category":"Nervous System Diseases","mesh_heading":"Hippocampal Sclerosis","scope_note":"Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY."},
{":id":"row-s3fk~uwv5.5jm4",":version":"rv-arfd-xdkz_9mgg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C10","tree_category":"Nervous System Diseases","mesh_heading":"Mixed Dementias","scope_note":"Dementias caused by multiple etiologies, e.g., ALZHEIMER DISEASE, and VASCULAR DEMENTIA and/or LEWY BODY DISEASE."},
{":id":"row-r7ph~d7g8-id4k",":version":"rv-ffuf_4t26.kxbp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Ventricular Outflow Obstruction, Left","scope_note":"Occlusion of the outflow tract in the LEFT VENTRICLE of the heart."},
{":id":"row-c64k_rfag-9f86",":version":"rv-amfe~naf6-jrmb",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C11","tree_category":"Eye Diseases","mesh_heading":"Congenital Cranial Dysinnervation Disorders","scope_note":"Congenital neurodevelopmental diseases characterized by abnormal eye, eyelid, and facial movements. Congenital cranial dysinnervation disorders (CCDDs) are caused by abnormal innervation of CRANIAL NERVES (e.g., CNs III, IV and VI) resulting in aplasia or hypoplasia of the ocular and facial musculature involved in EYE MOVEMENTS."},
{":id":"row-tcwx-za2g~5ez8",":version":"rv-fadh-37h2~4qwn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C11","tree_category":"Eye Diseases","mesh_heading":"Lagophthalmos","scope_note":"Inability to close eyelids completely."},
{":id":"row-z3fp~a3wj~khrr",":version":"rv-fyh4.yax4~nifz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C11","tree_category":"Eye Diseases","mesh_heading":"Limbal Stem Cell Deficiency","scope_note":"Loss or disturbance of limbal STEM CELL function in the CORNEAL LIMBUS resulting in inability to self-renew CORNEAL EPITHELIUM and conjunctivalized corneal surface."},
{":id":"row-enm3_e5vg~pcnf",":version":"rv-y8ic-ptfe~3z3j",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C11","tree_category":"Eye Diseases","mesh_heading":"Meibomitis","scope_note":"An inflammation of MEIBOMIAN GLANDS."},
{":id":"row-q6pz.9jhp~5cmi",":version":"rv-jpzu-e9ts.88ey",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C11","tree_category":"Eye Diseases","mesh_heading":"Polypoidal Choroidal Vasculopathy","scope_note":"A CHOROID neovascularization characterized by serosanguineous retinal pigment epithelial detachment and leakage of serous exudate sometimes associated with aneurysmal polypoidal lesions."},
{":id":"row-5yse-gts9-edcp",":version":"rv-6agd.kkvj_p87n",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C12","tree_category":"Urogenital Diseases","mesh_heading":"Bicornuate Uterus","scope_note":"A congenital uterine anomaly in which the UTERUS is divided into two uterine horns with a significant cleft at the uterine fundus due to partial fusion of the MULLERIAN DUCTS. Bicornuate uterus is sometimes associated with a longitudinal vaginal septum and abnormal development of renal tracts."},
{":id":"row-nimk~wtrz.zxk2",":version":"rv-pui7-8986-nkff",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C12","tree_category":"Urogenital Diseases","mesh_heading":"Chronic Kidney Diseases of Uncertain Etiology","scope_note":"Chronic kidney diseases not associated with traditional RISK FACTORS, e.g., TYPE 2 DIABETES MELLITUS and HYPERTENSION, but rather with infectious diseases, exposure to environmental toxins, or other unknown factors. They are most prevalent in agricultural communities of DEVELOPING COUNTRIES."},
{":id":"row-pabx~ggsi~dint",":version":"rv-dhds_hrmk-geug",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C12","tree_category":"Urogenital Diseases","mesh_heading":"Non-Muscle Invasive Bladder Neoplasms","scope_note":"A urothelial carcinoma found in the tissue that lines the inner surface of the bladder. The bladder muscle is not involved."},
{":id":"row-ctr8~uw4w-eb8j",":version":"rv-wuyv-86ca-5i6j",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C12","tree_category":"Urogenital Diseases","mesh_heading":"Septate Uterus","scope_note":"A congenital duplication of the UTERUS in which a septum is formed separating the uterus. The partitioning septum can also separate the CERVIX and VAGINA."},
{":id":"row-qq3n-6tfd.7hkj",":version":"rv-djmc_ge64~ribc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C12","tree_category":"Urogenital Diseases","mesh_heading":"Uterine Didelphys","scope_note":"An abnormality in which the MULLARIAN DUCTS do not properly join to form a single uterus during embryological development instead resulting in complete duplication of uterine horns and duplication of the cervix. Double uterus is associated with double cervix and vagina and sometimes renal agenesis."},
{":id":"row-tjtr-bu8k.6mk4",":version":"rv-pnmq~8zn2-t9gq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C12","tree_category":"Urogenital Diseases","mesh_heading":"Uterine Duplication Anomalies","scope_note":"A group of anomalies in which the UTERUS is duplicated due to abnormal fusion of the MULLERIAN DUCT during embryonic development."},
{":id":"row-st9f-xxek.wpvk",":version":"rv-dj5m~h3em_j8cs",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Acute Aortic Syndrome","scope_note":"A group of aortic diseases presented with acute chest pain. It commonly includes AORTIC DISSECTION; AORTIC INTRAMURAL HEMATOMA; PENETRATING ATHEROSCLEROTIC ULCER and sometimes aortic aneurysms."},
{":id":"row-vvh9~xfir_x5sw",":version":"rv-9gmn-x4hj.w23s",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Aneurysm, Aortic Arch","scope_note":"An abnormal balloon- or sac-like dilatation in the wall of the AORTIC ARCH."},
{":id":"row-9wit-fpaj-xuvr",":version":"rv-pzzr_ffp9_6cv9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Aneurysm, Ascending Aorta","scope_note":"An abnormal balloon- or sac-like dilatation in the wall of the ASCENDING AORTA."},
{":id":"row-ymd2~atty_pxuh",":version":"rv-cftm.ut83-9a2p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Aortic Aneurysm, Thoracoabdominal","scope_note":"An abnormal balloon- or sac-like dilatation in the wall of ABDOMINAL AORTA at the aortic hiatus."},
{":id":"row-7gur.p3hm_tnhs",":version":"rv-7qji_efbh~z2mn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Aortic Intramural Hematoma","scope_note":"An atypical form of AORTIC DISSECTION in which subintimal dissection of the aortic TUNICA MEDIA without initial laceration of the aortic TUNICA INTIMA. It may begin from a rupture of the VASA VASORUM feeding aortic media."},
{":id":"row-ja7y.cs4j-uzph",":version":"rv-jh5m.xacw~fbg9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Aortic Root Aneurysm","scope_note":"An abnormal balloon- or sac-like dilatation in the wall of the AORTIC ROOT."},
{":id":"row-7x7e~gewt~uqgp",":version":"rv-9axw.b4zb~yngc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Apical Hypertrophic Cardiomyopathy","scope_note":"A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as \"ace of spades\" sign), and deep T-wave inversions in EKG. Clinical symptoms include minor symptoms such as CHEST PAIN; DYSPNEA; and SYNCOPE to more complex symptoms such as ATRIAL FIBRILLATION; VENTRICULAR FIBRILLATION; MYOCARDIAL INFARCTION and CONGESTIVE HEART FAILURE. A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY."},
{":id":"row-yffi_n3sc_u2v3",":version":"rv-m3p3.mc5e_jhh4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Descending Thoracic Aortic Aneurysm","scope_note":"An abnormal balloon- or sac-like dilatation in the wall of the DESCENDING THORACIC AORTA."},
{":id":"row-eg5t-wxze~qte7",":version":"rv-jhgr.rypm_7gmm",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Dissection, Abdominal Aorta","scope_note":"Dissection or a tear of the ABDOMINAL AORTA. It includes thoracoabdominal aortic dissection at the aortic hiatus."},
{":id":"row-kucf.zpvb.im8k",":version":"rv-dbhr.56db_xrai",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Dissection, Ascending Aorta"},
{":id":"row-jp2x-n5tv_h4bg",":version":"rv-7g6p-a2rx-wsgd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Dissection, Blood Vessel","scope_note":"A tear or separation of the layers by a blood vessel typically involving vessels under pressure, i.e., ARTERIES, e.g., AORTA. Tearing of the TUNICA INTIMA layer of a blood vessel may lead to interstitial HEMORRHAGE. Dissection between the tunica intima and TUNICA MEDIA causes luminal occlusion. Dissection at the media, or between the media and the outer ADVENTITIA causes aneurismal dilation."},
{":id":"row-bim8.texb-c77b",":version":"rv-sv8e~avsu~ifgp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Dissection, Thoracic Aorta","scope_note":"Dissection or a tear of the THORACIC AORTA. It includes aortic root dissection, ascending aortic dissection, aortic arch dissection and descending thoracic aortic dissection."},
{":id":"row-78wm.zgm6_rykf",":version":"rv-kh6i~qqj7~4r9p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Ehlers-Danlos Syndrome, Type IV","scope_note":"A subtype of Ehlers-Danlos syndrome (EDS) characterized by vascular pathologies, e.g., AORTIC DISSECTION in addition to common EDS findings, e.g., hyperextensible skin and joints, skin fragility and reduced wound healing capability. It is associated with mutations in collagen type III alpha 1 chain gene (COLLAGEN TYPE III)."},
{":id":"row-phn6.muz7~4quv",":version":"rv-7cef~7izd~dain",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Isolated Systolic Hypertension","scope_note":"Hypertension with elevated systolic and normal diastolic blood pressure. It is the most common subtype in the elderly and is related to VASCULAR STIFFNESS and ATHEROSCLEROTIC PLAQUE buildup."},
{":id":"row-vpu9-qqeh_d4w3",":version":"rv-tam6~ef46-72ux",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Penetrating Atherosclerotic Ulcer","scope_note":"Ulceration of the AORTA by an ATHEROSCLEROTIC PLAQUE by penetrating through and disrupting the internal elastic lamina of the TUNICA INTIMA."},
{":id":"row-c87d_5zcn~swe3",":version":"rv-enf8~d9e8_zhik",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Popliteal Artery Aneurysm","scope_note":"An abnormal balloon- or sac-like dilatation in the wall of the POPLITEAL ARTERY located behind the KNEE JOINT."},
{":id":"row-f2w8.m7xt-ydx9",":version":"rv-qg3n-etws_gkyn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C14","tree_category":"Cardiovascular Diseases","mesh_heading":"Ventricular Outflow Obstruction, Right","scope_note":"Occlusion of the outflow tract in the RIGHT VENTRICLE of the heart."},
{":id":"row-ahm7~rpbm~yk25",":version":"rv-44r5-cmec_gmu7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C15","tree_category":"Hemic and Lymphatic Diseases","mesh_heading":"Ehlers-Danlos Syndrome, Type IV","scope_note":"A subtype of Ehlers-Danlos syndrome (EDS) characterized by vascular pathologies, e.g., AORTIC DISSECTION in addition to common EDS findings, e.g., hyperextensible skin and joints, skin fragility and reduced wound healing capability. It is associated with mutations in collagen type III alpha 1 chain gene (COLLAGEN TYPE III)."},
{":id":"row-3ewv~ntnf-y3t6",":version":"rv-94pb-hp34-zke3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Congenital Cranial Dysinnervation Disorders","scope_note":"Congenital neurodevelopmental diseases characterized by abnormal eye, eyelid, and facial movements. Congenital cranial dysinnervation disorders (CCDDs) are caused by abnormal innervation of CRANIAL NERVES (e.g., CNs III, IV and VI) resulting in aplasia or hypoplasia of the ocular and facial musculature involved in EYE MOVEMENTS."},
{":id":"row-ymqs.pnj3.7fer",":version":"rv-psxv~jcx6_arz5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Dental Enamel Hypomineralization","scope_note":"Reduced mineralization disorder of the DENTAL ENAMEL during development resulting in qualitative defects, e.g., discolored or chalky (soft) enamel."},
{":id":"row-shnc.hi2p_6nu7",":version":"rv-8h4c.2mwq-2wv2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Developmental Defects of Enamel","scope_note":"Defects in normal AMELOGENESIS caused by any local, systemic, environmental, or genetic factors. Enamel defects resulting from demineralization of normally developed DENTAL ENAMEL is referred to as TOOTH DEMINERALIZATION."},
{":id":"row-tzeg-z7jq_u3wq",":version":"rv-hmg7_puiu_7rc4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Ehlers-Danlos Syndrome, Type IV","scope_note":"A subtype of Ehlers-Danlos syndrome (EDS) characterized by vascular pathologies, e.g., AORTIC DISSECTION in addition to common EDS findings, e.g., hyperextensible skin and joints, skin fragility and reduced wound healing capability. It is associated with mutations in collagen type III alpha 1 chain gene (COLLAGEN TYPE III)."},
{":id":"row-k5ev_cakj.s57w",":version":"rv-cvnn-iufp~3c6v",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Focal Cortical Dysplasia","scope_note":"Abnormal, non-neoplastic cell proliferation of the CEREBRAL CORTEX confined to an area in any lobe. Focal cortical dysplasia in the temporal lobe is associated with TEMPORAL LOBE EPILEPSY."},
{":id":"row-uex2.n494.hjwx",":version":"rv-cj5b~kutb_k9h7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Hippocampal Sclerosis","scope_note":"Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY."},
{":id":"row-svja-3s6v.wks8",":version":"rv-3r37-uz27_x45u",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Molar Hypomineralization","scope_note":"A type of developmental disturbance of AMELOGENESIS involving MOLARS of any type (obligatory) plus other teeth sometimes. It is characterized by demarcated enamel opacities with unknown systemic causation (idiopathic)."},
{":id":"row-2m9r_utbe-2vi8",":version":"rv-qs6s_6sv2.s8qh",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Pancreas Divisum","scope_note":"Anatomic variants in PANCREATIC DUCTS characterized by failure of fusion of the ventral and dorsal endodermal buds. Pancreas divisum results in inadequate or no communication between dorsal and ventral ducts. While most cases are asymptomatic, it may be associated with recurrent PANCREATITIS."},
{":id":"row-dfb7~ka47.qdpn",":version":"rv-r2de~chmd~9jwb",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C16","tree_category":"Congenital, Hereditary, and Neonatal Diseases and Abnormalities","mesh_heading":"Uterine Duplication Anomalies","scope_note":"A group of anomalies in which the UTERUS is duplicated due to abnormal fusion of the MULLERIAN DUCT during embryonic development."},
{":id":"row-7kzx_eigw~snxe",":version":"rv-jd4f-hnd7.3u8t",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C17","tree_category":"Skin and Connective Tissue Diseases","mesh_heading":"Calcinosis Cutis","scope_note":"Pathological deposition of calcium in the skin and subcutaneous tissue. Excessive calcification of the skin may be associated with underlying diseases that cause tissue damage (e.g., EHLERS-DANLOS SYNDROME; PSEUDOXANTHOMA ELASTICUM; ROTHMUND-THOMSON SYNDROME; and WERNER SYNDROME) or that cause abnormal calcium and phosphate metabolism (e.g., CALCIPHYLAXIS; CHRONIC KIDNEY FAILURE; HYPERPARATHYROIDISM; and SARCOIDOSIS)."},
{":id":"row-ef6p_krqa~hqqi",":version":"rv-znrt_amu9~y45q",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C17","tree_category":"Skin and Connective Tissue Diseases","mesh_heading":"Chronic Inducible Urticaria","scope_note":"Chronic urticaria with identified triggering factor which is either physical, e.g., vibratory urticaria, or non-physical, e.g., aquagenic urticaria."},
{":id":"row-a5vw_s5a3~c2ja",":version":"rv-8b6a.t3vp~8mmz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C17","tree_category":"Skin and Connective Tissue Diseases","mesh_heading":"Ehlers-Danlos Syndrome, Type IV","scope_note":"A subtype of Ehlers-Danlos syndrome (EDS) characterized by vascular pathologies, e.g., AORTIC DISSECTION in addition to common EDS findings, e.g., hyperextensible skin and joints, skin fragility and reduced wound healing capability. It is associated with mutations in collagen type III alpha 1 chain gene (COLLAGEN TYPE III)."},
{":id":"row-4cf4_ybsk_y3b4",":version":"rv-rqkk_unk4-hihx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C17","tree_category":"Skin and Connective Tissue Diseases","mesh_heading":"Urticaria, Solar","scope_note":"Chromophore-dependent photodermatosis triggered by UV and visible light."},
{":id":"row-fe7r~re26_56p2",":version":"rv-23x6~erty~r79q",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C18","tree_category":"Nutritional and Metabolic Diseases","mesh_heading":"Calcinosis Cutis","scope_note":"Pathological deposition of calcium in the skin and subcutaneous tissue. Excessive calcification of the skin may be associated with underlying diseases that cause tissue damage (e.g., EHLERS-DANLOS SYNDROME; PSEUDOXANTHOMA ELASTICUM; ROTHMUND-THOMSON SYNDROME; and WERNER SYNDROME) or that cause abnormal calcium and phosphate metabolism (e.g., CALCIPHYLAXIS; CHRONIC KIDNEY FAILURE; HYPERPARATHYROIDISM; and SARCOIDOSIS)."},
{":id":"row-f5av.mhtz.vgpw",":version":"rv-vqdh_7xsb-tnf2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Allergic Fungal Sinusitis","scope_note":"Fungal infection in the PARANASAL SINUSES characterized by common allergy respiratory symptoms, recurrent NASAL POLYPS and/or ASTHMA with buildup of allergic MUCIN."},
{":id":"row-gepa-dia4-4xrr",":version":"rv-7ss9~e8ff_y9jj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Bronchiolitis Obliterans Syndrome","scope_note":"Bronchiolitis obliterans complication from allogenic HEMATOPOIETIC STEM CELL TRANSPLANTATION and LUNG TRANSPLANTATION."},
{":id":"row-d3cz~nsgb_un54",":version":"rv-iij3.y46f_ab29",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Chronic Inducible Urticaria","scope_note":"Chronic urticaria with identified triggering factor which is either physical, e.g., vibratory urticaria, or non-physical, e.g., aquagenic urticaria."},
{":id":"row-5v3v-wqw9~m9fi",":version":"rv-xhhr-aaq2_rd87",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Drug Fever","scope_note":"Drug-induced fever."},
{":id":"row-yi57~68cf.4u8t",":version":"rv-3c9e~zt98.h5bd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Dust Mite Allergy","scope_note":"Allergic rhinitis due to HOUSE DUST MITE ALLERGENS (e.g., Der p 1 of HOUSE DUST MITES) that is triggered by the immune system."},
{":id":"row-xich-7f94-8gs2",":version":"rv-zuxk~97cv-wmp3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Exercise-Induced Allergies","scope_note":"Allergic reactions following a period of exercise. Elevated serum HISTAMINE and TRYPTASE levels and cutaneous MAST CELL degranulation are often associated with post-exertional allergic reactions which sometimes are triggered only in combination with prior consumption of a specific food such as wheat. Allergic symptoms produced post-exercise range from skin eruption, asthma, bronchospasm, and anaphylaxis."},
{":id":"row-ce9j~hvaa.nrwi",":version":"rv-2i3k-auw9~7tgi",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Urticaria, Solar","scope_note":"Chromophore-dependent photodermatosis triggered by UV and visible light."},
{":id":"row-pr52_8gwd.94t9",":version":"rv-9idf.uaa5_ntkr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C20","tree_category":"Immune System Diseases","mesh_heading":"Venom Hypersensitivity","scope_note":"Allergic reaction to venoms in insect bites and stings that is triggered by the immune system (i.e., HISTAMINE RELEASE)."},
{":id":"row-iyvm-ncsn_mf9h",":version":"rv-wu3x_fb96.ygb6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Aortic Intramural Hematoma","scope_note":"An atypical form of AORTIC DISSECTION in which subintimal dissection of the aortic TUNICA MEDIA without initial laceration of the aortic TUNICA INTIMA. It may begin from a rupture of the VASA VASORUM feeding aortic media."},
{":id":"row-eyv2~x3px~fwhq",":version":"rv-3ujn~qb7d_33sx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Breakthrough Infections","scope_note":"Infections by the same infectious agent (e.g., virus, fungus) occurring during exposure to prophylaxis, vaccine and treatment."},
{":id":"row-zh9b-vy75_ueir",":version":"rv-ub6q~v7mh_4c2p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Chronic Inducible Urticaria","scope_note":"Chronic urticaria with identified triggering factor which is either physical, e.g., vibratory urticaria, or non-physical, e.g., aquagenic urticaria."},
{":id":"row-x9sx_inpt.v7r5",":version":"rv-zgwx-j7f8.dpw4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Chronic Kidney Diseases of Uncertain Etiology","scope_note":"Chronic kidney diseases not associated with traditional RISK FACTORS, e.g., TYPE 2 DIABETES MELLITUS and HYPERTENSION, but rather with infectious diseases, exposure to environmental toxins, or other unknown factors. They are most prevalent in agricultural communities of DEVELOPING COUNTRIES."},
{":id":"row-vzym.h43g.a2s5",":version":"rv-heyy_amaj_aq6x",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Crystalluria","scope_note":"Crystals in the URINE found in urinary sediment analysis. Urinary crystalline may be formed from various metabolites (e.g., CALCIUM OXALATES; CALCIUM PHOSPHATES; URATES) and drugs (e.g., SULPHADIAZINE; ACYCLOVIR; and TRIAMTERENE)."},
{":id":"row-b7cb~pkn6-z5jc",":version":"rv-4pxu-tcpy.g6gv",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Dropped Head Syndrome","scope_note":"Condition characterized by sagging of the head due to severe NECK MUSCLES weakness in the back of the neck. It may result in severe cervical KYPHOSIS called chin-on-chest deformity. Dropped head syndrome is most often associated with other diseases, e.g., PARKINSON'S DISEASE; STROKES; HEAD AND NECK CANCER; and ANKYLOSING SPONDYLITIS."},
{":id":"row-m3f9~pva7~cqnp",":version":"rv-9ty7-42wj.gd32",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Drug Fever","scope_note":"Drug-induced fever."},
{":id":"row-hyc6~rygb_5y78",":version":"rv-be46.4f2h_3xvf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Low Anterior Resection Syndrome","scope_note":"Postoperative complication after removal of the RECTUM (low anterior resection surgery or resection surgery to the lower part of the COLON). It includes disordered rectum function, e.g., frequent BOWEL MOVEMENT; FECAL INCONTINENCE; and CONSTIPATION."},
{":id":"row-4wrq-4n4k-twgm",":version":"rv-54vh.7rs8_nkcg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Overtraining Syndrome","scope_note":"An accumulation of training and/or non-training stress resulting in short-term decrement in performance capacity with or without related physiological and psychological signs and symptoms of maladaptation in which restoration of performance capacity may take from several weeks to several months.(from  Curr Sports Med Rep. May-Jun 2015;14(3):157-8)"},
{":id":"row-4txp_mxvs~7j6k",":version":"rv-mh9p.ifig.a4ds",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Platypnea Orthodeoxia Syndrome","scope_note":"Orthostatic dyspnea and fall of oxygen blood saturation when standing up which regress by assuming lying position."},
{":id":"row-tc4i_hx8d.3smq",":version":"rv-6s3h_vzcx~26qg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Polypoidal Choroidal Vasculopathy","scope_note":"A CHOROID neovascularization characterized by serosanguineous retinal pigment epithelial detachment and leakage of serous exudate sometimes associated with aneurysmal polypoidal lesions."},
{":id":"row-kdh4~u367-qbc9",":version":"rv-k8sn~euuc~bf55",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Post-Acute COVID-19 Syndrome","scope_note":"Post acute stage of COVID-19 virus infection. Persistent symptoms may include FATIGUE; DYSPNEA; and MEMORY LOSS."},
{":id":"row-7vv2~jqzn-xifb",":version":"rv-hm5k_6mgf-nxi7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Post-Infectious Disorders","scope_note":"Debilitating disorder characterized by fatigue and other symptoms related to cognitive, autonomous, and immune dysfunction experienced in the aftermath of infections."},
{":id":"row-84mq.hbk4.estd",":version":"rv-ydxz_n29q.5sdc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C23","tree_category":"Pathological Conditions, Signs and Symptoms","mesh_heading":"Urticaria, Solar","scope_note":"Chromophore-dependent photodermatosis triggered by UV and visible light."},
{":id":"row-2deu~hkbj.r4dd",":version":"rv-b3e3.2p93_e2sf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C24","tree_category":"Occupational Diseases","mesh_heading":"Chronic Kidney Diseases of Uncertain Etiology","scope_note":"Chronic kidney diseases not associated with traditional RISK FACTORS, e.g., TYPE 2 DIABETES MELLITUS and HYPERTENSION, but rather with infectious diseases, exposure to environmental toxins, or other unknown factors. They are most prevalent in agricultural communities of DEVELOPING COUNTRIES."},
{":id":"row-ghtw-c7kz~ksk2",":version":"rv-stxm-kdgb.rpyf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C25","tree_category":"Chemically-Induced Disorders","mesh_heading":"Drug Fever","scope_note":"Drug-induced fever."},
{":id":"row-98y8.2r47~e85m",":version":"rv-xx6d~4njz_rxnb",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Elbow Fractures","scope_note":"Fractures of the distal HUMERUS and the proximal ULNA and the RADIUS at the ELBOW JOINT, including the head, anatomic and surgical necks, and tuberosities."},
{":id":"row-evjw~vp7v-zmm8",":version":"rv-piqs~vg43~k9b6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Elbow Injuries","scope_note":"Injuries involving the ELBOW and ELBOW JOINT."},
{":id":"row-r2mr.9rqk.q8gd",":version":"rv-vsce~wprm-up63",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Femoral Fractures, Distal","scope_note":"Fractures of the distal FEMUR from the articular surface in the KNEE to the condylar region of the femur. A subset with a coronal-plane fracture of the distal femur condyle(s) is Hoffa Fracture."},
{":id":"row-d2xe_y99a.qgcd",":version":"rv-y7bw_pw7k.t979",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Fibula Fractures","scope_note":"Fractures of the FIBULA."},
{":id":"row-vjtk~bm9y-iusk",":version":"rv-47ew.vkr3~d2h5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Hoffa Fracture","scope_note":"Coronal plane fractures of the FEMUR condyle at the KNEE."},
{":id":"row-73yp.3vji~45jd",":version":"rv-8573_fva2-phe7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Humeral Fractures, Distal","scope_note":"Fractures of the distal HUMERUS at the ELBOW JOINT."},
{":id":"row-hx2i-8djh_wsk5",":version":"rv-nfxh~d2yr-577r",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Knee Fractures","scope_note":"Fractures of bones at the KNEE and the KNEE JOINT."},
{":id":"row-ra8b.mzpd-5x9h",":version":"rv-qmgs.c5mq.mfg6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Multiple Amputations, Traumatic","scope_note":"The loss of part of, or all of, more than one limb, or other appendages of the body due to injury or disease."},
{":id":"row-s9kr_rqbh_4n6a",":version":"rv-3qsi.5cvu-pgam",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Olecranon Fracture","scope_note":"Fractures of the OLECRANON PROCESS at the ELBOW JOINT."},
{":id":"row-7qm7-8p6k_g56b",":version":"rv-zdmv_tzjc~64zp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Patella Fracture","scope_note":"Fractures of the PATELLA."},
{":id":"row-f427~kp5m~82jx",":version":"rv-jgtb.tudi~ye66",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Proximal Femoral Fractures","scope_note":"Fractures of the proximal FEMUR at the HIP."},
{":id":"row-2q4n~8byg.jjtu",":version":"rv-25nt~bfzr.g4f4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Radial Head and Neck Fractures","scope_note":"Fractures of the proximal head and/or neck of the RADIUS bone near the ELBOW JOINT."},
{":id":"row-s8vj_3thw-ak6k",":version":"rv-fnxg~emzw~kxx8",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Tibial Plateau Fractures","scope_note":"Fractures in the proximal portion of the TIBIA which acts as articular surface in the KNEE. They are often associated with knee ligament injuries (e.g., ACL TEARS)."},
{":id":"row-etv7_ex62_wrjf",":version":"rv-mg9a~dfc7_867y",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"C26","tree_category":"Wounds and Injuries","mesh_heading":"Wrist Fractures","scope_note":"Fractures of the CARPAL BONES, the distal ULNA and/or RADIUS at the WRIST."},
{":id":"row-g6ch_737t_a2q5",":version":"rv-8irp-kegh-2e5z",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D02","tree_category":"Organic Chemicals","mesh_heading":"Betulinic Acid","scope_note":"A lupane-type triterpene derivative of betulin which was originally isolated from BETULA or birch tree. It has anti-inflammatory, anti-HIV and antineoplastic activities."},
{":id":"row-zfvm.cdps.cuim",":version":"rv-mgjs.r2bd~d38h",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D02","tree_category":"Organic Chemicals","mesh_heading":"Lupanes","scope_note":"Pentacyclic triterpenes with isopropyl and its derivatives at the C19 position. It is initially biosynthesized by cyclization of oxidosqualene to lupeol."},
{":id":"row-vgsh_kr9g~7w6f",":version":"rv-7m36-5erh_j9ne",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D02","tree_category":"Organic Chemicals","mesh_heading":"Synthetic Cathinone","scope_note":"A propiophenone derivative chemically related to cathinone, a substance found in the KHAT plant."},
{":id":"row-qffq~pgdz-kutf",":version":"rv-emyw.vwnz.v2zv",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D03","tree_category":"Heterocyclic Compounds","mesh_heading":"Gemcitabine","scope_note":"A deoxycytidine antimetabolite used as an antineoplastic agent."},
{":id":"row-6ynn~7iwu_ivh7",":version":"rv-eecb-pw2q~vicy",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D03","tree_category":"Heterocyclic Compounds","mesh_heading":"Matrines","scope_note":"Tetracyclic bis-quinolizidine alkaloids found in the family LEGUMINOSAE, mainly in the genus SOPHORA."},
{":id":"row-nguu.2zg3-ref6",":version":"rv-23zw_vyjj_4gp8",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D03","tree_category":"Heterocyclic Compounds","mesh_heading":"Quinolizidine Alkaloids","scope_note":"Alkaloids containing QUINOLIZIDINE ring structure. They are found in the genistoid legumes of FABACEAE (formerly Leguminosae) including genera LUPINUS and SOPHORA."},
{":id":"row-i5w3.paxk_gw3t",":version":"rv-iuxv.8xzr~6suz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D05","tree_category":"Macromolecular Substances","mesh_heading":"Polyhydroxybutyrates","scope_note":"A thermostable biopolymer with repeating hydroxybutyryl units. It is typically the most abundant polyhydroxyalkanoate in microbes with PHA granules."},
{":id":"row-rngx_syh3-5kw2",":version":"rv-iyh4-k7nn.cxtj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D06","tree_category":"Hormones, Hormone Substitutes, and Hormone Antagonists","mesh_heading":"Anabolic Androgenic Steroids","scope_note":"Synthetic, or human-made, variations of the male sex hormone testosterone often misused by athletes to enhance performance."},
{":id":"row-4mna_wybz.er9p",":version":"rv-ykp5~kdy7.ctr4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"Axl Receptor Tyrosine Kinase","scope_note":"A member of the Tyro3-Axl-Mer (TAM) RECEPTOR PROTEIN-TYROSINE KINASES subfamily. Involved in several cellular functions including growth, migration, cell aggregation, and anti-inflammation."},
{":id":"row-k3gc_ziiv~xkc8",":version":"rv-g48r_n547.56vu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"beta-D-Galactoside alpha 2-6-Sialyltransferase","scope_note":"Sialyltransferases that catalyze the transfer of N-ACETYLNEURAMINIC ACID from CYTIDINE MONOPHOSPHATE N-ACETYLNEURAMINIC ACID to the 6-OH of the GALACTOSE residue of N-GLYCANS."},
{":id":"row-zhyh.62x2~qc58",":version":"rv-en8k-wu4g.4ua8",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"beta-Galactoside alpha-2,3-Sialyltransferase","scope_note":"Sialyltransferases that catalyze the transfer of N-ACETYLNEURAMINIC ACID from CYTIDINE MONOPHOSPHATE N-ACETYLNEURAMINIC ACID to the 3-OH of the GALACTOSE residue of N-GLYCANS."},
{":id":"row-6225~vzw3.cxr4",":version":"rv-38aj-68v4_xtk7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"Cyclin-Dependent Kinase-Activating Kinase","scope_note":"A highly-conserved cyclin-dependent kinase that activates other CYCLIN DEPENDENT KINASES and plays a key role in regulation of the CELL CYCLE."},
{":id":"row-5khf-wq2j-ba4c",":version":"rv-7w2m-vkub_gj9p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"DNA Polymerase iota","scope_note":"A highly error-prone DNA polymerase. It is a member of the Y-family of DNA polymerases that are DNA DAMAGE tolerant and involved in translesion DNA synthesis. DNA polymerase iota is an orthologue of yeast Rad30. Its replication fidelity is template dependent and favors Hoogsteen base-pairing at its active site."},
{":id":"row-u9hb~jcdp-qbsi",":version":"rv-yb5k~rdbb~vzzp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"Glutathione Peroxidase GPX1","scope_note":"One of the most abundant isoenzymes of the glutathione peroxidase family. Located in the cytosol and mitochondria, it catalyzes the reduction of HYDROGEN PEROXIDE to water,  functioning to limit the accumulation of hydrogen peroxide and modulating processes that utilize hydrogen peroxide; and also the reduction of other organic hydroperoxides to their corresponding alcohols."},
{":id":"row-b4s5.xq2i_tyqe",":version":"rv-tnt8.zyrn_5avg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D08","tree_category":"Enzymes and Coenzymes","mesh_heading":"Prorenin Receptor","scope_note":"Single-pass transmembrane receptor protein that plays an important role in ANGIOTENSIN II production and cellular responses to RENIN."},
{":id":"row-meus_kxmr.zyxz",":version":"rv-vreb-pms3-2h7t",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D09","tree_category":"Carbohydrates","mesh_heading":"Dietary Advanced Glycation End Products","scope_note":"Advanced glycation end products (AGEs) present in food. They are absorbed by the GASTROINTESTINAL SYSTEM and contribute to the body's total AGEs. The food BROWNING REACTION, such as occurs during food processing or cooking with high heat (frying, broiling, grilling, roasting, etc.) accelerates the formation of AGEs in food."},
{":id":"row-kj2i-mrcu~3whk",":version":"rv-b3r8-9har~da8s",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D09","tree_category":"Carbohydrates","mesh_heading":"Glycated Proteins","scope_note":"Advanced glycation end products formed from the spontaneous, non-enzymatic reaction of sugars with free amino groups in proteins. In the past, a glycosylated protein sometimes referred to a glycated protein.  GLYCOSYLATED PROTEINS is now restricted to proteins glycosylated by GLYCOSYLTRANSFERASES or via specialized organic chemistry reactions."},
{":id":"row-hzyx~j3im.3bab",":version":"rv-azyx_7dqn_jj3j",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D09","tree_category":"Carbohydrates","mesh_heading":"Glycated Serum Albumin","scope_note":"Serum albumin that has undergone, in vivo, spontaneous, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA."},
{":id":"row-w6um-knbj-r2ee",":version":"rv-mmcq.29tp_px37",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D09","tree_category":"Carbohydrates","mesh_heading":"Glycated Serum Proteins","scope_note":"Proteins in serum that have undergone, in vivo, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA."},
{":id":"row-u3h2.99ur-3wcy",":version":"rv-a26x_y6ty~jcpy",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D10","tree_category":"Lipids","mesh_heading":"Polyhydroxybutyrates","scope_note":"A thermostable biopolymer with repeating hydroxybutyryl units. It is typically the most abundant polyhydroxyalkanoate in microbes with PHA granules."},
{":id":"row-jxjk.jweq.ifpj",":version":"rv-cen5~y9hx.mw4h",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Axl Receptor Tyrosine Kinase","scope_note":"A member of the Tyro3-Axl-Mer (TAM) RECEPTOR PROTEIN-TYROSINE KINASES subfamily. Involved in several cellular functions including growth, migration, cell aggregation, and anti-inflammation."},
{":id":"row-kii5-3g2k.yte3",":version":"rv-egrx_d9v8.j87z",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Bromodomain Containing Proteins","scope_note":"Non-histone chromosomal proteins that regulate GENE EXPRESSION through a variety of mechanisms including recognizing acetylated HISTONE LYSINE residues and through transcriptional machinery regulation."},
{":id":"row-vuqu_nzy7_hjnb",":version":"rv-sxbc-xwsb.rv8u",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Combined Antibody Therapeutics","scope_note":"Combinations of monoclonal antibodies used therapeutically to modulate the IMMUNE SYSTEM."},
{":id":"row-e5h3-mku8_xraw",":version":"rv-wzmr.n4s7_hdys",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Cyclin-Dependent Kinase-Activating Kinase","scope_note":"A highly-conserved cyclin-dependent kinase that activates other CYCLIN DEPENDENT KINASES and plays a key role in regulation of the CELL CYCLE."},
{":id":"row-98ey~gr7q_i6e9",":version":"rv-vbs9~wcph_5e82",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Delta Catenin","scope_note":"A CATENIN protein that plays a critical role in cell adhesion and tissue morphogenesis by regulating the surface stability of C-, E-, and N- CADHERINS."},
{":id":"row-uiwa_sdq5.wbme",":version":"rv-v97i.4bhe.kx8e",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Gasdermins","scope_note":"A  family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER."},
{":id":"row-kvck-ak26-m8jx",":version":"rv-hvr5~hxrm_gdkw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Glutathione Peroxidase GPX1","scope_note":"One of the most abundant isoenzymes of the glutathione peroxidase family. Located in the cytosol and mitochondria, it catalyzes the reduction of HYDROGEN PEROXIDE to water,  functioning to limit the accumulation of hydrogen peroxide and modulating processes that utilize hydrogen peroxide; and also the reduction of other organic hydroperoxides to their corresponding alcohols."},
{":id":"row-us7t-jj8v-vax6",":version":"rv-bie6~qedy~cuhs",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Glycated Proteins","scope_note":"Advanced glycation end products formed from the spontaneous, non-enzymatic reaction of sugars with free amino groups in proteins. In the past, a glycosylated protein sometimes referred to a glycated protein.  GLYCOSYLATED PROTEINS is now restricted to proteins glycosylated by GLYCOSYLTRANSFERASES or via specialized organic chemistry reactions."},
{":id":"row-wufs-r7m4~dw3f",":version":"rv-z5fk.h4pp.jd3w",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Glycated Serum Albumin","scope_note":"Serum albumin that has undergone, in vivo, spontaneous, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA."},
{":id":"row-ttbp.fsgs_mdp2",":version":"rv-hwrk.v4rv.jwzu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Glycated Serum Proteins","scope_note":"Proteins in serum that have undergone, in vivo, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA."},
{":id":"row-cudn_ncxq.budm",":version":"rv-jf26.tckw_axa5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Interferon Lambda","scope_note":"A specific type of interferon that is similar to  INTERFERON TYPE I. It primarily functions at barrier epithelial surface, such as the respiratory tract and blood brain barrier"},
{":id":"row-eg7s-svk9~4bpa",":version":"rv-5ccv-yusy_8ryg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Lymphocyte Activation Gene 3 Protein","scope_note":"A CD4-related protein with high affinity cell surface binding to MHC class II. It functions in downregulation of T cell proliferation following binding to MHC class II molecules."},
{":id":"row-4hxb~cezz~xbfx",":version":"rv-dwxn~tpsj.7n6i",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Nociceptin Receptor","scope_note":"A member of the opioid subfamily of the G PROTEIN-COUPLED RECEPTORS. It is the receptor for the endogenous neuropeptide nociceptin. It functions in modulating NOCICEPTION and the perception of pain."},
{":id":"row-f5qj.pf4b.8tcb",":version":"rv-64di.q6vk_ukcf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Prorenin Receptor","scope_note":"Single-pass transmembrane receptor protein that plays an important role in ANGIOTENSIN II production and cellular responses to RENIN."},
{":id":"row-23h2_qkvy_h2nj",":version":"rv-ph9y-xq5k.gdhe",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Secreted Frizzled-Related Proteins","scope_note":"Soluble and secreted frizzled-related proteins which function as modulators of WNT SIGNALING PATHWAY."},
{":id":"row-c92k_xsw6.rfrt",":version":"rv-tx48~9hge~fzcr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Seminal Proteins","scope_note":"Proteins found in semen. Seminal proteins are composed of SEMINAL PLASMA PROTEINS and SPERM PROTEINS."},
{":id":"row-d2kn_7g7s.3ehp",":version":"rv-jrkd~nchq.f7m4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Sperm Proteins","scope_note":"Proteins found in sperm. Sperm-specific proteins have important roles in FERTILIZATION including SPERM MOTILITY and SPERM-OVUM INTERACTIONS. Sperm-specific proteins are also important for early EMBRYO DEVELOPMENT."},
{":id":"row-ency.ycqi~qfa9",":version":"rv-4rc5-rquh.bxy8",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D12","tree_category":"Amino Acids, Peptides, and Proteins","mesh_heading":"Thymic Stromal Lymphopoietin","scope_note":"A pleiotropic cytokine involved in INFLAMMATION and immunoregulation. Thymic stromal lymphopoietin can activate MAST CELLS; DENDRITIC CELLS; and T-LYMPHOCYTES, and is produced by various cell types, including epithelial and dendritic cells.."},
{":id":"row-2227-d66d_nps5",":version":"rv-xqf2~am7n~h7sr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D13","tree_category":"Nucleic Acids, Nucleotides, and Nucleosides","mesh_heading":"Piwi-Interacting RNA","scope_note":"A  class of small RNAs that are 24–31 nucleotides in length. They associate with  the PIWI SUBFAMILY OF ARGONAUTE PROTEINS to form effector complexes known as piRNA-induced silencing complexes, which repress transposons via transcriptional or posttranscriptional mechanisms and maintain germline genome integrity. In addition to their  role in transposon silencing, piRNAs in diverse organisms function in the regulation of cellular genes."},
{":id":"row-ewc6.2cwe~wm64",":version":"rv-jyna~nrru-cck6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D13","tree_category":"Nucleic Acids, Nucleotides, and Nucleosides","mesh_heading":"RNA, Guide, CRISPR-Cas Systems","scope_note":"A component of CRISPR-Cas SYSTEMS. Cas endodeoxyribonucleases assemble with a guide RNA complex, a hybrid of CRISPR RNA (crRNA) and transactivating crRNA (tracrRNA) molecules, to form an active complex that cleaves DNA. crRNA and tracrRNA can be synthetically fused into a single RNA molecule, namely single guide RNA. Synthetic sgRNA is used with CRISPR-Cas SYSTEMS for targeted GENE EDITING."},
{":id":"row-ftny.wh5z_7cz4",":version":"rv-cndn~8aw9.3nhj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D13","tree_category":"Nucleic Acids, Nucleotides, and Nucleosides","mesh_heading":"Subgenomic RNA","scope_note":"RNA that results from VIRUS REPLICATION of partial genomic regions. The process may involve specific internal transcriptional initiation and termination sites."},
{":id":"row-2xy9-h596~bu8a",":version":"rv-24ty-33sr.7s34",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Dietary Advanced Glycation End Products","scope_note":"Advanced glycation end products (AGEs) present in food. They are absorbed by the GASTROINTESTINAL SYSTEM and contribute to the body's total AGEs. The food BROWNING REACTION, such as occurs during food processing or cooking with high heat (frying, broiling, grilling, roasting, etc.) accelerates the formation of AGEs in food."},
{":id":"row-z39r~xip3.dxes",":version":"rv-cihn.kgry.p87i",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Glycated Proteins","scope_note":"Advanced glycation end products formed from the spontaneous, non-enzymatic reaction of sugars with free amino groups in proteins. In the past, a glycosylated protein sometimes referred to a glycated protein.  GLYCOSYLATED PROTEINS is now restricted to proteins glycosylated by GLYCOSYLTRANSFERASES or via specialized organic chemistry reactions."},
{":id":"row-y8sn-4iey_9aiy",":version":"rv-bhtj_r4ct~evbp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Glycated Serum Albumin","scope_note":"Serum albumin that has undergone, in vivo, spontaneous, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA."},
{":id":"row-wxp2.neue.acm7",":version":"rv-i9hc.z23g~dhb9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Glycated Serum Proteins","scope_note":"Proteins in serum that have undergone, in vivo, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA."},
{":id":"row-3gze-i56t.mukf",":version":"rv-mnc8_zbkb~zbqi",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Interferon Lambda","scope_note":"A specific type of interferon that is similar to  INTERFERON TYPE I. It primarily functions at barrier epithelial surface, such as the respiratory tract and blood brain barrier"},
{":id":"row-eepj.5n3k-5yvf",":version":"rv-x85f_uzuc-capq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Lymphocyte Activation Gene 3 Protein","scope_note":"A CD4-related protein with high affinity cell surface binding to MHC class II. It functions in downregulation of T cell proliferation following binding to MHC class II molecules."},
{":id":"row-5xg2~zuuk-k7je",":version":"rv-rtix~p2zx_6946",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Phytoalexins","scope_note":"Secondary metabolites produced and accumulated by plants infected with microbial pathogen or otherwise under abiotic stress. Phytoalexins are structurally diverse but in common play a role in triggering PLANT SYSTEMIC ACQUIRED RESISTANCE."},
{":id":"row-w466-u6g3_iasv",":version":"rv-h3km~qkmf-zxws",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Electroporation Therapies","scope_note":"Treatment modalities that use pulsed electrical currents to permeabilize cell membranes and thereby enhance uptake of substances into cells of the body."},
{":id":"row-83tp~zqf7~pira",":version":"rv-z5z8~gdr8.i9c5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D23","tree_category":"Biological Factors","mesh_heading":"Thymic Stromal Lymphopoietin","scope_note":"A pleiotropic cytokine involved in INFLAMMATION and immunoregulation. Thymic stromal lymphopoietin can activate MAST CELLS; DENDRITIC CELLS; and T-LYMPHOCYTES, and is produced by various cell types, including epithelial and dendritic cells.."},
{":id":"row-sq6a_p3jr-azrr",":version":"rv-2vj3.e22i.q6ig",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D25","tree_category":"Biomedical and Dental Materials","mesh_heading":"Phytosomes","scope_note":"Lipid-based vesicular drug delivery systems that are structurally related to LIPOSOMES. Unlike LIPOSOMES, PHYTOSOMES have their active ingredient as a part of their lipid membrane itself."},
{":id":"row-6qyg~dj7d-reg4",":version":"rv-ub8c.pfwv_2u5h",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D26","tree_category":"Pharmaceutical Preparations","mesh_heading":"Combined Antibody Therapeutics","scope_note":"Combinations of monoclonal antibodies used therapeutically to modulate the IMMUNE SYSTEM."},
{":id":"row-9djm_t9zv_8bb5",":version":"rv-xak8_v33r_hg8p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D26","tree_category":"Pharmaceutical Preparations","mesh_heading":"Phytosomes","scope_note":"Lipid-based vesicular drug delivery systems that are structurally related to LIPOSOMES. Unlike LIPOSOMES, PHYTOSOMES have their active ingredient as a part of their lipid membrane itself."},
{":id":"row-rp8f.2u4g-m47d",":version":"rv-ukxx-ueud~vpmu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"Antiglycation Agents","scope_note":"Compounds that reduce the non-enzymatic glycation of proteins, lipids, and nucleic acids AND thus reducing the formation of ADVANCED GLYCATION END-PRODUCTS."},
{":id":"row-q4vc.tnc9~5f3z",":version":"rv-hcye~9din.ia93",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"Insulin Secretagogues","scope_note":"Hypoglycemic agents that stimulate INSULIN SECRETION from the PANCREATIC BETA CELL to decrease postprandial BLOOD GLUCOSE."},
{":id":"row-ygxf-t3e3_e4sd",":version":"rv-6u9b~fwa8-9npy",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"Interleukin-6 Inhibitors","scope_note":"Immunosuppressive agents which inhibit the action of INTERLEUKIN-6."},
{":id":"row-y694_4kpz-4amw",":version":"rv-tsga~ymt7_v3fx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"PPAR-gamma Agonists","scope_note":"Hypoglycemic agents that specifically target PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA. They increase tissue sensitivity to the insulin action and are used to treat TYPE 2 DIABETES MELLITUS."},
{":id":"row-3jpa~jnym-yigd",":version":"rv-25dk.uf33.6xnj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"Proteolysis Targeting Chimera","scope_note":"Bifunctional molecules that are designed to recruit E3 UBIQUITIN LIGASE to a specific target protein. Proteolysis targeting chimera consist of a target protein ligand connected via a linker to an E3 ligand. They promote association of E3 with specific target proteins tagged for degradation via the PROTEASOME."},
{":id":"row-nyie.ufss_upqn",":version":"rv-8htf~tzjx~ebk9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"Renin Inhibitors","scope_note":"Agents that inhibit the activity of RENIN and cause VASODILATION."},
{":id":"row-fxrm-pkgb~t74z",":version":"rv-zv3j.bwnd~n2kn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"D27","tree_category":"Chemical Actions and Uses","mesh_heading":"Tyrosine Protein Kinase Inhibitors","scope_note":"Protein kinase inhibitors that inhibit TYROSINE PROTEIN KINASES."},
{":id":"row-54qj_pb84_i24p",":version":"rv-itaj_wmws~qb4n",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Clinical Relevance","scope_note":"Criteria to determine whether a finding (e.g., clinical examination, lab test, imaging results) requires a medical intervention for meaningful improvement in outcome often to avoid OVERDIAGNOSIS and/or OVERTREATMENT."},
{":id":"row-rdix-4qpb_jfvp",":version":"rv-7hj8~yygy~hf4q",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Comprehensive Metabolic Panel","scope_note":"A series of blood tests on one panel that measure the body's chemical balance and metabolism."},
{":id":"row-fcuv-s7gy_g9bb",":version":"rv-8h53~rtha-iyqw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Dopaminergic Imaging","scope_note":"Functional brain imaging techniques that utilize various RADIONUCLIDE TRACERS that bind to different targets in the SYNAPSES of DOPAMINERGIC NEURONS."},
{":id":"row-uns5~t6mc_w23c",":version":"rv-pqia_q8pt~7wsq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Local Field Potential Measurement","scope_note":"Recording of brain electrical activities recorded by a small-size electrode in the brain. It measures electric potential in the extracellular medium around neurons generated by small electric currents of local origin."},
{":id":"row-geiq~yc5j-x65c",":version":"rv-zfij~wwah~7sae",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Microphysiological Systems","scope_note":"Devices designed to recapitulate tissue or organ-level physiology and architect by combining MICROFLUIDICS; MICROFABRICATION; and 3D CELL CULTURE. Microphysiological systems mimic interconnections important in physiological or pathophysiological states of organ(s) and are often used for instance in HIGH THROUGHPUT SCREENING of drugs and factors important in disease modeling."},
{":id":"row-48vw_qp8b.9guv",":version":"rv-rhrw_3pgx-mnm9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Motion Capture","scope_note":"Technological process of recording the MOTION and MOVEMENT of objects (e.g., surgical instrument in robotic surgery), body parts (e.g., EYE MOVEMENT), animals or people."},
{":id":"row-smxx.ni4w-a3an",":version":"rv-jzam-qzdb~whhr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Nerve Conduction Studies","scope_note":"Electrical tests to analyze the function of peripheral nerves by measuring various characteristics of NERVE CONDUCTION such as amplitude, velocity, and latency."},
{":id":"row-jtua_75zb_kdgn",":version":"rv-975c.gwyc_9ug4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Rapid Diagnostic Tests","scope_note":"Diagnostic assays designed for use at the point-of-care (POC) that can be adapted for use in low-resource settings. These tests are low-cost, simple to operate and read, sensitive, specific, stable at high temperatures, and works in a short period of time."},
{":id":"row-c6te.a6z8.xy9t",":version":"rv-ardy.ieqi.n92h",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Ultrasonography, Carotid Arteries","scope_note":"Ultrasound imaging of the CAROTID ARTERIES to measure their morphological components such as arterial wall shape and thickness; ATHEROSCLEROTIC PLAQUE; and STENOSIS. BLOOD CIRCULATION in the carotid is visualized via DOPPLER ULTRASONOGRAPHY."},
{":id":"row-xuiu~5g3g_vasc",":version":"rv-hjpp~i4n2-3xw9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Urinary Sediment Analysis","scope_note":"Microscopic visualization and/or chemical analysis of the sediments in URINE."},
{":id":"row-9egx-hhrb-vcwx",":version":"rv-db4b.6pbs.jysm",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E01","tree_category":"Diagnosis","mesh_heading":"Volume Electron Microscopy","scope_note":"Electron microscopy techniques designed to reconstruct 3-D images at micrometer volume scales at nanometer (nm) level resolutions. Volume electron microscopy uses various techniques to render, segment and reconstruct 3-D images from stacked sequential 2-D images of incremental z-planes."},
{":id":"row-d3t2-y7bv.xs7c",":version":"rv-kzk7_udfi.8adq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Anticoagulation Bridge","scope_note":"A peri-operative bridge therapy procedure in patients with high risk THROMBOEMBOLIC events and the risk of bleeding."},
{":id":"row-2d4t~gacy_kmeq",":version":"rv-9q4h-4q45-j9bu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Blood Banking","scope_note":"The administrative procedures and methods required for collecting, characterizing and storing blood or plasma in BLOOD BANKS."},
{":id":"row-k6be~p4fk.u4gy",":version":"rv-n5xr~duhb~cpb8",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Bridge Therapy","scope_note":"Treatment used in a transition between former and new therapeutic regimes."},
{":id":"row-db93_2dsi_kxcu",":version":"rv-3au9.uqhr-kiu9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Cognitive Training","scope_note":"A non-pharmacological form of treatment focusing on guided practice on tasks that target specific cognitive functions. These functions include memory, attention, and problem-solving. (from Cochrane.org/CD013069/DEMENTIA_cognitive-training-people-mild-moderate-dementia)"},
{":id":"row-w5su.uxiu_bkq5",":version":"rv-fhz4.3xu8~fe2f",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Corneal Cross-Linking","scope_note":"An ophthalmic treatment used to prevent weakening or bulging of the CORNEA in corneal ECTASIA, e.g., post-LASIK ectasia, KERATOCONUS and pellucid marginal corneal degeneration. It uses UV-A and RIBOFLAVIN to crosslink and strengthen COLLAGEN fibers within the cornea."},
{":id":"row-4ktk-za2h.p2r4",":version":"rv-9x8u~wu73~4jc4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"COVID-19 Drug Treatment","scope_note":"The use of DRUGS to treat COVID19 or its symptoms."},
{":id":"row-ce5y.axe4-k5pj",":version":"rv-ppuz~ju2x~sfvx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"COVID-19 Serotherapy","scope_note":"Transfer of blood plasma derived from patients who have recovered from COVID-19 to non-immune hosts."},
{":id":"row-5fcs~fcmj.69ag",":version":"rv-qjy6.jfkz-hab9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Irreversible Electroporation Therapy","scope_note":"The use of a dose of electricity that causes the pores that are formed  in CELL MEMBRANES during ELECTROPORATION to remain open long enough to trigger CELL DEATH. It is sometimes used in conjunction with ELECTROCHEMOTHERAPY."},
{":id":"row-8ywn_rvvd.kbex",":version":"rv-2dug~2uud~duq2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E02","tree_category":"Therapeutics","mesh_heading":"Olfactory Training","scope_note":"A non-surgical and non-pharmacological exercise treatment designed to  manage OLFACTORY DISORDERS."},
{":id":"row-dnz4~zv64~mpbu",":version":"rv-rhvg~7u5u-btna",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E04","tree_category":"Surgical Procedures, Operative","mesh_heading":"Endovascular Aneurysm Repair","scope_note":"Endovascular surgery used to treat an AORTIC ANEURYSM. It involves implanting an endovascular stent graft around dilated vessel area reinforcing the wall and creating an artificial lumen through which blood can circulate bypassing aneurysm sac."},
{":id":"row-zd9u.42wp-sagt",":version":"rv-fri7-xvje-7bjm",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E04","tree_category":"Surgical Procedures, Operative","mesh_heading":"Penile Transplantation","scope_note":"Surgical transference of the PENIS (or the PENIS and SCROTUM together) as a complete organ and the composite of many tissue types, from one individual to another."},
{":id":"row-94ag.dfmy_bs4d",":version":"rv-nxag.4exp-jefm",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E04","tree_category":"Surgical Procedures, Operative","mesh_heading":"Phalloplasty","scope_note":"Surgery to restore, reconstruct, or improve the shape or appearance of a damaged, misshapen, or missing PENIS due to injury, disease, or developmental abnormalities."},
{":id":"row-ffef.62gk.jg39",":version":"rv-9wf2_wga3~uzza",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E04","tree_category":"Surgical Procedures, Operative","mesh_heading":"Tattoo Removal","scope_note":"Procedures to remove a tattoo. They may include laser surgery, excisional surgery, dermabrasion, or application of topical agents."},
{":id":"row-kmvn_cf9k_7ic5",":version":"rv-ymxg_ttr4.z258",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E04","tree_category":"Surgical Procedures, Operative","mesh_heading":"Transurethral Resection of Bladder","scope_note":"Surgical removal of tumor in the BLADDER with resectoscope inserted through the URETHRA."},
{":id":"row-ia9f~wcpg_wram",":version":"rv-su2p.bhhd.akem",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Blood Banking","scope_note":"The administrative procedures and methods required for collecting, characterizing and storing blood or plasma in BLOOD BANKS."},
{":id":"row-gths~vvq5-mpan",":version":"rv-igw5.tq9a.intd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Capillary Isoelectric Focusing","scope_note":"Isoelectric focusing in capillary gels instead of slab gels. Capillary gel electrophoresis generally allows higher resolution, higher detection sensitivity and easier integration with other separation and detection techniques."},
{":id":"row-dpbz_g2tt-vg3h",":version":"rv-uifc_2383~jjvx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Comprehensive Metabolic Panel","scope_note":"A series of blood tests on one panel that measure the body's chemical balance and metabolism."},
{":id":"row-mi53.fpx4_kt84",":version":"rv-6apz.d7ex_s9ae",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"COVID-19 Serotherapy","scope_note":"Transfer of blood plasma derived from patients who have recovered from COVID-19 to non-immune hosts."},
{":id":"row-eduh.rcn5~dm5c",":version":"rv-hh7h~w6pz_dz7b",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Dopaminergic Imaging","scope_note":"Functional brain imaging techniques that utilize various RADIONUCLIDE TRACERS that bind to different targets in the SYNAPSES of DOPAMINERGIC NEURONS."},
{":id":"row-ma7w.jeny_c6c5",":version":"rv-r45m-vqpg-krra",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Electroporation Therapies","scope_note":"Treatment modalities that use pulsed electrical currents to permeabilize cell membranes and thereby enhance uptake of substances into cells of the body."},
{":id":"row-4jjv_52fi.vuyk",":version":"rv-csr9.pfbn~t7ke",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Information Motivation Behavioral Skills Model","scope_note":"A model for understanding patient behaviors, recognizes three constructs—information, motivation, and behavioral skills—needed to engage in a given health behavior, as specific individual determinants of behavior and behavioral change (Fisher & Fisher; Norton, 2009)."},
{":id":"row-7v8u-iyn8_fqr4",":version":"rv-frm2-6d6q_s2xh",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Irreversible Electroporation Therapy","scope_note":"The use of a dose of electricity that causes the pores that are formed  in CELL MEMBRANES during ELECTROPORATION to remain open long enough to trigger CELL DEATH. It is sometimes used in conjunction with ELECTROCHEMOTHERAPY."},
{":id":"row-hvjy-tuiw-j9d2",":version":"rv-k5cx.i8wm_pr72",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Microphysiological Systems","scope_note":"Devices designed to recapitulate tissue or organ-level physiology and architect by combining MICROFLUIDICS; MICROFABRICATION; and 3D CELL CULTURE. Microphysiological systems mimic interconnections important in physiological or pathophysiological states of organ(s) and are often used for instance in HIGH THROUGHPUT SCREENING of drugs and factors important in disease modeling."},
{":id":"row-nuwg_wxv6.ps5w",":version":"rv-94a9.znx6.x2r7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Motion Capture","scope_note":"Technological process of recording the MOTION and MOVEMENT of objects (e.g., surgical instrument in robotic surgery), body parts (e.g., EYE MOVEMENT), animals or people."},
{":id":"row-z8m2_7ae2~k8sy",":version":"rv-zifg~d55h_u627",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Obesity Paradox","scope_note":"An observation that high BODY MASS INDEX is sometimes associated with lower CARDIOVASCULAR DISEASE mortality in certain population, e.g., ELDERLY."},
{":id":"row-x868.yxza.vgw3",":version":"rv-6g25~bpgc~ct9c",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Pharmacophore","scope_note":"A three-dimensional representation of a molecule that is used for modeling recognition of ligands and macromolecular targets."},
{":id":"row-nqwv-8n4y_w7cd",":version":"rv-9cy5-qxub.w2pv",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Rapid Diagnostic Tests","scope_note":"Diagnostic assays designed for use at the point-of-care (POC) that can be adapted for use in low-resource settings. These tests are low-cost, simple to operate and read, sensitive, specific, stable at high temperatures, and works in a short period of time."},
{":id":"row-mh3m~352i~922e",":version":"rv-xyfz-7sz6_z3q2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Ribosome Profiling","scope_note":"A technique of mRNA sequence analysis that is used to determine which mRNAs are being actively translated. This technique relies on sequencing of RIBOSOME protected mRNA fragments (so-called ribosomal footprints) allowing the indication of the exact positions of ribosomes on transcripts."},
{":id":"row-uaq8.ecp2~umnw",":version":"rv-5isk_k9mz_fvg6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Secondary Data Analysis","scope_note":"Analysis or reanalysis of existing data collected by someone else usually  for a different purpose."},
{":id":"row-emhu_j27f_epv8",":version":"rv-bc8e.ythc-cnkr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Single-Cell Gene Expression Analysis","scope_note":"Assaying the products of GENETIC TRANSCRIPTION in individual cells."},
{":id":"row-xa5u_3r4i_5xku",":version":"rv-z6d8-t62k-zvbs",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Theory of Planned Behavior","scope_note":"The construct in which intentions to perform behaviors of different kinds can be predicted with high accuracy from attitudes toward the behavior, subjective norms, and perceived behavioral control; and these intentions, together with perceptions of behavioral control, account for considerable variance in actual behavior. (from Ajzen, Organizational Behavior and Human Decision Processes, V.50, Issue 2, p.179-211.)"},
{":id":"row-q8w9_a5dk-f9nw",":version":"rv-twsh-se87~3j8c",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Urinary Sediment Analysis","scope_note":"Microscopic visualization and/or chemical analysis of the sediments in URINE."},
{":id":"row-av42-tr8v~kmd8",":version":"rv-vg2i_u3a9_67yd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E05","tree_category":"Investigative Techniques","mesh_heading":"Volume Electron Microscopy","scope_note":"Electron microscopy techniques designed to reconstruct 3-D images at micrometer volume scales at nanometer (nm) level resolutions. Volume electron microscopy uses various techniques to render, segment and reconstruct 3-D images from stacked sequential 2-D images of incremental z-planes."},
{":id":"row-azx7-rzvh-t8an",":version":"rv-arwp-smfc-dz7z",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G06","tree_category":"Microbiological Phenomena","mesh_heading":"RNA Replication","scope_note":"The process by which a VIRAL RNA molecule is duplicated."},
{":id":"row-93sa.cmau_j5if",":version":"rv-ksg9~rr9u-6k85",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E07","tree_category":"Equipment and Supplies","mesh_heading":"Microphysiological Systems","scope_note":"Devices designed to recapitulate tissue or organ-level physiology and architect by combining MICROFLUIDICS; MICROFABRICATION; and 3D CELL CULTURE. Microphysiological systems mimic interconnections important in physiological or pathophysiological states of organ(s) and are often used for instance in HIGH THROUGHPUT SCREENING of drugs and factors important in disease modeling."},
{":id":"row-cwq4_uvak.nqd7",":version":"rv-jucc-x3kk-6m59",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"E07","tree_category":"Equipment and Supplies","mesh_heading":"Motorized Mobility Scooter","scope_note":"A device ridden while seated that usually has three or four wheels, is typically propelled by an electric motor, and is used by those with limited or impaired mobility."},
{":id":"row-fzmd~i596_5s77",":version":"rv-jq6z_n9s6-29e6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Chronotype","scope_note":"The natural inclination or preference of time of day in which an individual or an organism has the most activity, particularly as it relates to sleeping pattern and circadian sleep-wake preferences."},
{":id":"row-ixsy.92my~wsrb",":version":"rv-n27j-if4n.pjct",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Collective Efficacy","scope_note":"A group belief and perception in its ability to complete a task successfully. It includes shared belief it can control deviant behavior of a member."},
{":id":"row-dnih.yzvq_ygm2",":version":"rv-g995_ddf4~txuc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Extended Family","scope_note":"A household with members of at least three generations."},
{":id":"row-6z2n~rnx9-m88h",":version":"rv-iw6k_4n6a-m4id",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Family Structure","scope_note":"Structural nature of relationships among members of a household typically in reference to a MINOR residing in the same home. More broadly any organizational framework that determines family membership, and the functions and hierarchical position of family members (https://eric.ed.gov/?qt=Family+Structure&ti=Family+Structure)."},
{":id":"row-msvy~wniz.hxrw",":version":"rv-mq6a_gagf_i6ga",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Family Support","scope_note":"Support systems that provide assistance and encouragement between and among members of a FAMILY."},
{":id":"row-j75t_48ww_be6t",":version":"rv-ddp8.8qds_n4yt",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Group Dynamics","scope_note":"Processes of change in any social group from formation to functioning. It includes various forces that drive relationship among members and interaction with other groups."},
{":id":"row-9wu8.ac96-z59e",":version":"rv-dp9u~zg84-39wj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Intermittent Fasting","scope_note":"Alternating between fasting for an extended period of time during the day and eating during a restricted time for the day."},
{":id":"row-qbx8-fpz6~ikf4",":version":"rv-m4gj.xnhx_xhfs",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Kinesiophobia","scope_note":"Anxiety disorder of persistent and irrational fear of movement following an injury. It is related to perceived disability due to injury and CATASTROPHIZING in fear of (anticipated) PAIN and possibility of REINJURY."},
{":id":"row-9shr.uzhd.rkdm",":version":"rv-ypn3~irgd-nz2g",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Psychological Well-Being","scope_note":"Condition of existence, or state of awareness, in which psychological needs are satisfied"},
{":id":"row-4wsz~x3jr.7xxp",":version":"rv-ngew-ac99~vssr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F01","tree_category":"Behavior and Behavior Mechanisms","mesh_heading":"Suicide Prevention","scope_note":"Specific strategies for averting suicides. These include mental HEALTH PROMOTION and monitoring PSYCHOLOGICAL WELL-BEING and other intervention programs targeting susceptible individuals."},
{":id":"row-r2ts-gcva_xxh4",":version":"rv-3gv7~f784.p385",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F02","tree_category":"Psychological Phenomena","mesh_heading":"Processing Speed","scope_note":"The time it takes to understand and do a mental task. Unlike REACTION TIME processing speed does not necessarily include a motor component in response. Processing speed is tested by most NEUROPSYCHOLOGICAL TESTS."},
{":id":"row-43fb_irsq.32kq",":version":"rv-2cjv_qycz.vsyq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F02","tree_category":"Psychological Phenomena","mesh_heading":"Sleep Duration","scope_note":"Total number of hours of sleep in a day."},
{":id":"row-buhk~6y9k-29wg",":version":"rv-qiri_dafg-kat6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F02","tree_category":"Psychological Phenomena","mesh_heading":"Theory of Planned Behavior","scope_note":"The construct in which intentions to perform behaviors of different kinds can be predicted with high accuracy from attitudes toward the behavior, subjective norms, and perceived behavioral control; and these intentions, together with perceptions of behavioral control, account for considerable variance in actual behavior. (from Ajzen, Organizational Behavior and Human Decision Processes, V.50, Issue 2, p.179-211.)"},
{":id":"row-6n23.ddy6~pne2",":version":"rv-cn54-5abw-nu8z",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F03","tree_category":"Mental Disorders","mesh_heading":"Kinesiophobia","scope_note":"Anxiety disorder of persistent and irrational fear of movement following an injury. It is related to perceived disability due to injury and CATASTROPHIZING in fear of (anticipated) PAIN and possibility of REINJURY."},
{":id":"row-2hb8-mfpz_jei5",":version":"rv-i93w~3mrt~4yui",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F03","tree_category":"Mental Disorders","mesh_heading":"Military Sexual Trauma","scope_note":"Physical and psychological injuries resulting from SEXUAL VIOLENCE during MILITARY service."},
{":id":"row-mvjs.puyz_4szj",":version":"rv-xaim.fvn4-dfnq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"F03","tree_category":"Mental Disorders","mesh_heading":"Mixed Dementias","scope_note":"Dementias caused by multiple etiologies, e.g., ALZHEIMER DISEASE, and VASCULAR DEMENTIA and/or LEWY BODY DISEASE."},
{":id":"row-8vic~pfn5-r2aq",":version":"rv-exit_vjpp~gxuc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G01","tree_category":"Physical Phenomena","mesh_heading":"Partial Weight-Bearing","scope_note":"The  state of supporting a body to simulate partial or applied load."},
{":id":"row-sywi_9f6s_p9v5",":version":"rv-87y3.gxqk~p6bt",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G02","tree_category":"Chemical Phenomena","mesh_heading":"Carbohydrate Binding Modules","scope_note":"Contiguous amino acid sequences within a carbohydrate-active enzyme with discrete folds having carbohydrate binding activity. They are classified into 43 different families based on AMINO ACID SEQUENCE, binding specificity, and structure."},
{":id":"row-zh3s_p67h_hnkf",":version":"rv-d8dj_6mnv-zxi4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G02","tree_category":"Chemical Phenomena","mesh_heading":"Ribosome Shunting","scope_note":"Viral mechanisms of translational programming in which ribosomes reach the start codon bypassing or shunting over large segments of the 5′ UTR of  VIRAL RNA. Ribosome shunting allows host translational machinery to engage polycistronic transcripts similar to RIBOSOMAL FRAMESHIFTING, and use of INTERNAL RIBOSOME ENTRY SITES."},
{":id":"row-83y3_hwg9~gta7",":version":"rv-9pdh_jsw4-5p32",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G02","tree_category":"Chemical Phenomena","mesh_heading":"RNA Replication","scope_note":"The process by which a VIRAL RNA molecule is duplicated."},
{":id":"row-kq7t-nen5-hssv",":version":"rv-pe57.8n8u_rhnv",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G03","tree_category":"Metabolism","mesh_heading":"Proteotoxic Stress","scope_note":"Stressors and conditions which disturb PROTEOSTASIS. Dysfunctional responses to proteotoxic stress are associated with CELL DEATH; CELL SENESCENCE;  CANCER and PROTEINOPATHY."},
{":id":"row-8qk8-3vff.76uf",":version":"rv-jzjp~yjwk.9kjp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G03","tree_category":"Metabolism","mesh_heading":"Ribosome Shunting","scope_note":"Viral mechanisms of translational programming in which ribosomes reach the start codon bypassing or shunting over large segments of the 5′ UTR of  VIRAL RNA. Ribosome shunting allows host translational machinery to engage polycistronic transcripts similar to RIBOSOMAL FRAMESHIFTING, and use of INTERNAL RIBOSOME ENTRY SITES."},
{":id":"row-9z7b~djk9_ht9q",":version":"rv-vu23~vfqu~kfh4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G05","tree_category":"Genetic Phenomena","mesh_heading":"Epigenetic Memory","scope_note":"Various mechanisms by which a stable propagation of changes in gene expression that is passed from egg and sperm to the embryo persists via epigenetic changes, e.g., DNA METHYLATION pattern changes."},
{":id":"row-bu2g.e38w.q6t2",":version":"rv-85gg_qfuj.q5cp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G05","tree_category":"Genetic Phenomena","mesh_heading":"Ribosome Shunting","scope_note":"Viral mechanisms of translational programming in which ribosomes reach the start codon bypassing or shunting over large segments of the 5′ UTR of  VIRAL RNA. Ribosome shunting allows host translational machinery to engage polycistronic transcripts similar to RIBOSOMAL FRAMESHIFTING, and use of INTERNAL RIBOSOME ENTRY SITES."},
{":id":"row-6eyk~2gbw-z6uf",":version":"rv-bfi4~dspt~narq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G05","tree_category":"Genetic Phenomena","mesh_heading":"RNA Replication","scope_note":"The process by which a VIRAL RNA molecule is duplicated."},
{":id":"row-prh7_pwnc_hxbg",":version":"rv-cxsz_v8ag.hji2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G06","tree_category":"Microbiological Phenomena","mesh_heading":"Symbiont Induced Cytoplasmic Incompatibility","scope_note":"A naturally occurring reproductive phenomenon of INVERTEBRATES in which only certain combination of crosses result in viable embryos due to incompatibility between sperm and egg cells that is caused by differences in intracellular parasites (symbionts). For example, a maternally inherited symbiont bacteria, e.g., WOLBACHIA, induces changes in sperm of the host, causing mitotic defects in the fertilized embryo only in crosses between symbiotic males and females harboring a different or no symbiont."},
{":id":"row-dbsi_z94c-wdxd",":version":"rv-taqp_shhf_n8se",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Chronotype","scope_note":"The natural inclination or preference of time of day in which an individual or an organism has the most activity, particularly as it relates to sleeping pattern and circadian sleep-wake preferences."},
{":id":"row-hd72-j7pw~ebav",":version":"rv-n4eg~judc_trze",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Dietary Advanced Glycation End Products","scope_note":"Advanced glycation end products (AGEs) present in food. They are absorbed by the GASTROINTESTINAL SYSTEM and contribute to the body's total AGEs. The food BROWNING REACTION, such as occurs during food processing or cooking with high heat (frying, broiling, grilling, roasting, etc.) accelerates the formation of AGEs in food."},
{":id":"row-ee25.y8um_4y4t",":version":"rv-m9df~skei~4jvi",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Elimination Diets","scope_note":"Temporary dietary restrictions designed to help identify specific foods or FOOD ADDITIVES that trigger ALLERGIC REACTIONS, symptoms of DIGESTIVE SYSTEM DISORDERS, or other adverse food reactions."},
{":id":"row-unzb_d6gv_dg5f",":version":"rv-qkb5~87xv.q6hx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"FODMAP Diet","scope_note":"A type of elimination diet restricting from foods with fermentable oligosaccharides, disaccharides, monosaccharides, and polyols, to help determine if specific foods containing these carbohydrates are triggering symptoms of IRRITABLE BOWEL SYNDROME."},
{":id":"row-f5wm.c4bp.8maj",":version":"rv-3n59_nsdb-ka8h",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Food, Processed","scope_note":"Any raw agricultural commodity that has been subject to washing, cleaning, milling, cutting, chopping, heating, pasteurizing, blanching, cooking, canning, freezing, drying, dehydrating, mixing, packaging or other procedures that alter the food from its natural state. (from  A Guide to Federal Terms and Acronyms. Lanham, MD: Government Institutes.1991)"},
{":id":"row-t6pz-y2we_xvrc",":version":"rv-ce3n-qzxf_ksw5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Immunonutrition Diet","scope_note":"Diets supplemented with nutrients that beneficially stimulate the IMMUNE RESPONSE and improve control of inflammatory processes."},
{":id":"row-j3db_es85~stqb",":version":"rv-7emp_x6yd_8x4s",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Intermittent Fasting","scope_note":"Alternating between fasting for an extended period of time during the day and eating during a restricted time for the day."},
{":id":"row-8ef3~stf2_jeps",":version":"rv-bv9t-bm9m_2cuw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G07","tree_category":"Physiological Phenomena","mesh_heading":"Proteotoxic Stress","scope_note":"Stressors and conditions which disturb PROTEOSTASIS. Dysfunctional responses to proteotoxic stress are associated with CELL DEATH; CELL SENESCENCE;  CANCER and PROTEINOPATHY."},
{":id":"row-77jt_qkii~4bpm",":version":"rv-hmvk~fdif_kwqu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G09","tree_category":"Circulatory and Respiratory Physiological Phenomena","mesh_heading":"Global Longitudinal Strain","scope_note":"Global longitudinal strain (GLS) is a measure of ventricular function derived from 2-dimensional echocardiographic images by quantifying the relative length change in myocardial length between end-diastole and end-systole. GLS is used to predict cardiovascular outcomes and has been proposed to be a better measure of cardiac dysfunction than VENTRICULAR EJECTION FRACTION."},
{":id":"row-pc8q~azdd-d97p",":version":"rv-u6yn.bp8m-vmbx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G11","tree_category":"Musculoskeletal and Neural Physiological Phenomena","mesh_heading":"Sleep Duration","scope_note":"Total number of hours of sleep in a day."},
{":id":"row-bfng~wpwj_2ks3",":version":"rv-yumm~3myw~889t",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G12","tree_category":"Immune System Phenomena","mesh_heading":"Innate Immunity Recognition","scope_note":"Innate immunity systems which recognize presence of pathogens either through detection of damages associated with pathogen effector, e.g., pathogenic toxins and pore formation (effector triggered immunity) or though detection of molecular patterns common to many types of microbes (PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES) through PATTERN RECOGNITION RECEPTORS."},
{":id":"row-wsnv_8ja8_bgnt",":version":"rv-cgn4.drx5~8h2e",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G12","tree_category":"Immune System Phenomena","mesh_heading":"Plant Systemic Acquired Resistance","scope_note":"A plant defense mechanism in which a plant pathogen-associated molecular pattern effector is detected through various receptors, e.g., PATTERN RECOGNITION RECEPTORS, which in turn induces fortified, primed defense in plant immune reaction. It confers long lasting and long distance plant immune defense against a broad spectrum of pathogens using various plant defense hormones or metabolites, e.g., SALICYLIC ACID and N-HYDROXYPIPECOLIC ACID, as signals to distant leaves for heightened immune state to counteract and limit subsequent infection."},
{":id":"row-m6iq~wpt4_awe7",":version":"rv-fdfw.9ixb~bbhz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G12","tree_category":"Immune System Phenomena","mesh_heading":"T-Cell Exhaustion","scope_note":"Progressive deterioration of  T-cell function due to chronic antigen stimulation and inflammatory signals, e.g., CHRONIC INFECTION and CANCER. T-cell exhaustion is characterized by weakened immune system, e.g., dysfunctional MEMORY T CELLS differentiation and EPIGENETIC REPRESSION of IMMUNOLOGIC MEMORY effector functions."},
{":id":"row-p44e~7qt2~c8t8",":version":"rv-yysn.3vvw-tird",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G12","tree_category":"Immune System Phenomena","mesh_heading":"Trained Immunity","scope_note":"Ability of the INNATE IMMUNITY system to form IMMUNOLOGIC MEMORY and provide enhanced defense against subsequent secondary infections. In trained immunity, long-term adaptation of innate immune cells occurs through EPIGENETIC PROCESSES and metabolic CELLULAR REPROGRAMMING to form long term immunologic memory."},
{":id":"row-5x6s~z5ud-e5ip",":version":"rv-kjt9-dvtd~rpgr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G15","tree_category":"Plant Physiological Phenomena","mesh_heading":"Drought Resistance","scope_note":"The ability of a plant to adapt in a drought environment and tolerate a reduction in available water."},
{":id":"row-qy6h_t4h5~wejv",":version":"rv-eycn_m4rd_5z7y",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G15","tree_category":"Plant Physiological Phenomena","mesh_heading":"Plant Systemic Acquired Resistance","scope_note":"A plant defense mechanism in which a plant pathogen-associated molecular pattern effector is detected through various receptors, e.g., PATTERN RECOGNITION RECEPTORS, which in turn induces fortified, primed defense in plant immune reaction. It confers long lasting and long distance plant immune defense against a broad spectrum of pathogens using various plant defense hormones or metabolites, e.g., SALICYLIC ACID and N-HYDROXYPIPECOLIC ACID, as signals to distant leaves for heightened immune state to counteract and limit subsequent infection."},
{":id":"row-dsmz_bxi2.mcgf",":version":"rv-bq5u_8iuk~37fe",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G16","tree_category":"Biological Phenomena","mesh_heading":"Ocean Acidification","scope_note":"Reduction in OCEAN WATER overall pH. Ocean acidification is linked to CORAL BLEACHING and may disturb other marine BIODIVERSITY."},
{":id":"row-458u_7rji_f8ju",":version":"rv-2pnw.h7br~rgdu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G16","tree_category":"Biological Phenomena","mesh_heading":"Symbiont Induced Cytoplasmic Incompatibility","scope_note":"A naturally occurring reproductive phenomenon of INVERTEBRATES in which only certain combination of crosses result in viable embryos due to incompatibility between sperm and egg cells that is caused by differences in intracellular parasites (symbionts). For example, a maternally inherited symbiont bacteria, e.g., WOLBACHIA, induces changes in sperm of the host, causing mitotic defects in the fertilized embryo only in crosses between symbiotic males and females harboring a different or no symbiont."},
{":id":"row-kpcm.hen7_eytm",":version":"rv-bf8w-dm6w_ttxx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Middle Eastern People","scope_note":"People native to or inhabitants of MIDDLE EAST including BAHRAIN; IRAN; IRAQ; ISRAEL; JORDAN; KUWAIT; LEBANON; OMAN; PALESTINIAN TERRITORIES; QATAR; SAUDI ARABIA; SYRIA; TURKEY; UNITED ARAB EMIRATES; and YEMEN."},
{":id":"row-qsfi_zy6t-ejk9",":version":"rv-5a7h_tpjb.d7g4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"G17","tree_category":"Mathematical Concepts","mesh_heading":"Random Forest","scope_note":"An algorithm used in decision analysis and MACHINE LEARNING that uses a set of trees to combine output of multiple, randomly generated DECISION TREES. The final class of each tree is aggregated and evaluated by weighted values to construct the final classifier."},
{":id":"row-962u_hxtn_h9vx",":version":"rv-zhmx_f5mc.ndjc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Artificial Life","scope_note":"Research involving the synthesis of life and life-like phenomena and the application of such techniques toward the enhancement of our theoretical understanding of life and life-like phenomena, studied through the use of computer programs."},
{":id":"row-p7ib~rezj-8dnm",":version":"rv-xqku~etas-8rze",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Cytology","scope_note":"The study of single cell as a unit of living organisms. Cytopathology, a branch of this discipline, studies structural changes of cells in diseases and is used in diagnosing diseases."},
{":id":"row-6vmt_vusq_gs99",":version":"rv-z8tr_7ivp.wd67",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Document Analysis","scope_note":"A form of qualitative research that uses a systematic procedure to analyze documentary evidence and answer specific research questions."},
{":id":"row-b6sd.hr4h_qrwk",":version":"rv-hj4k_252m.h33s",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Evidence Gaps","scope_note":"Areas where little or no evidence from impact evaluations and SYSTEMATIC REVIEWS is available and where future research should be focused (from https://openknowledge.worldbank.org/handle/10986/16941)."},
{":id":"row-ebva~7aun-94ey",":version":"rv-qvyi.umim-72qi",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Multiomics","scope_note":"The study of a variety of omic data (TRANSCRIPTOME; PROTEOME; METABOLOME; etc.) generated from the same biological source such as a cell type or organ during normal versus diseased states."},
{":id":"row-c7e8.v95e-st9y",":version":"rv-mdhb-vkbn~5ygu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Multiomics","scope_note":"The study of a variety of omic data (TRANSCRIPTOME; PROTEOME; METABOLOME; MICROBIOME, etc.) as the data set generated from the same biological source such as a cell type or organ during normal versus diseased states."},
{":id":"row-kyd3.3qdr_k4jf",":version":"rv-kjch~idki~s264",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H01","tree_category":"Natural Science Disciplines","mesh_heading":"Secondary Data Analysis","scope_note":"Analysis or reanalysis of existing data collected by someone else usually  for a different purpose."},
{":id":"row-qgcj-96w6_u474",":version":"rv-tux7.xsiq-6qip",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H02","tree_category":"Health Occupations","mesh_heading":"Cognitive Training","scope_note":"A non-pharmacological form of treatment focusing on guided practice on tasks that target specific cognitive functions. These functions include memory, attention, and problem-solving. (from Cochrane.org/CD013069/DEMENTIA_cognitive-training-people-mild-moderate-dementia)"},
{":id":"row-tuxk~pbvn~mqqf",":version":"rv-smgk~68ps.836h",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H02","tree_category":"Health Occupations","mesh_heading":"Cytology","scope_note":"The study of single cell as a unit of living organisms. Cytopathology, a branch of this discipline, studies structural changes of cells in diseases and is used in diagnosing diseases."},
{":id":"row-hpwe.wu2i_bjsb",":version":"rv-3jk2_bj8s_jx94",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"H02","tree_category":"Health Occupations","mesh_heading":"Paramedicine","scope_note":"A domain of practice and health profession that specialises across a range of settings including, but not limited to, emergency and primary care. Paramedics work in a variety of clinical settings such as EMERGENCY MEDICAL SERVICES, ambulance services, hospitals and clinics as well as non-clinical roles, such as education, leadership, public health and research. PARAMEDICS possess complex knowledge and skills, a broad scope of practice and are an essential part of the healthcare system. Depending on location, paramedics may practice under medical direction or independently, often in unscheduled, unpredictable or dynamic settings. (from J Multidiscip Healthc 2021 Dec 30;14:3561-3570)"},
{":id":"row-qav7.8m75.5r6c",":version":"rv-hkep~h3fx_qb99",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Antiracism","scope_note":"Beliefs, actions or intentions, and policies that oppose RACISM or discrimination  based on RACE."},
{":id":"row-ki6g-z67x_s468",":version":"rv-ps8v-9mx9~7ffs",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Collective Efficacy","scope_note":"A group belief and perception in its ability to complete a task successfully. It includes shared belief it can control deviant behavior of a member."},
{":id":"row-8xq3.is94_7kqt",":version":"rv-s5ez.q7vm-h6us",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Diversity, Equity, Inclusion","scope_note":"Developing and ensuring compliance with laws, regulations, and policies that support civil rights, equity, diversity, and inclusion. Executive Order 13985 (Advancing Racial Equity and Support for Underserved Communities Through the Federal Government), which established that affirmatively advancing equity, civil rights, racial justice, and equal opportunity is the responsibility of the whole of our Government."},
{":id":"row-cn43_b3td~x9cs",":version":"rv-9vqn~gbiz~t52t",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Extended Family","scope_note":"A household with members of at least three generations."},
{":id":"row-jvw6~viwn_5rrm",":version":"rv-ghtt~ajy4-ipa7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Family Structure","scope_note":"Structural nature of relationships among members of a household typically in reference to a MINOR residing in the same home. More broadly any organizational framework that determines family membership, and the functions and hierarchical position of family members (https://eric.ed.gov/?qt=Family+Structure&ti=Family+Structure)."},
{":id":"row-mej3.x44m.iv8r",":version":"rv-pkb8_xpu2-gy96",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Family Support","scope_note":"Support systems that provide assistance and encouragement between and among members of a FAMILY."},
{":id":"row-mrkn~x9kj-6gaz",":version":"rv-765s~b2cr-kvry",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Forensic Microbiology","scope_note":"The scientific discipline dedicated to analyzing evidence from BIOTERRORISM, biocrime, HOAX, or inadvertent microorganism/toxin release for attribution purposes."},
{":id":"row-kz8h_rt58.qyzr",":version":"rv-gpa4~g4ii~xbfr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Low Socioeconomic Status","scope_note":"Socioeconomic status with relatively low income and/or assets (POVERTY) and EDUCATIONAL LEVEL."},
{":id":"row-vwvq_74ri~is6z",":version":"rv-d4j4-2ydx~phxb",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Psychological Well-Being","scope_note":"Condition of existence, or state of awareness, in which psychological needs are satisfied"},
{":id":"row-fyqv~unnw~hvh9",":version":"rv-j5am-hhdv_phv5",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Residential Segregation","scope_note":"Spatial separation of HOUSING within a geographic area based on racial, ethnic, nationality and other SOCIOECONOMIC FACTORS."},
{":id":"row-mvey.rcjr~cxjt",":version":"rv-4xd9.69h7_rbsq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Social Group","scope_note":"A collection of two or more people who share a common identity as defined by beliefs, codes of conduct, CULTURE and SOCIAL NORMS."},
{":id":"row-jhqw_utmd_imp6",":version":"rv-7x6m.8fyz_emgp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Socioeconomic Disparities in Health","scope_note":"Differences in health based on socioeconomic status. Socioeconomic-based health disparities often begins early in life due to various SOCIOECONOMIC FACTORS, e.g. social, economic and educational statuses that limit potential or realized access to resources for maintaining health."},
{":id":"row-zddw-ucrf_fyh9",":version":"rv-ibnt~5uq7_5v5i",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Suicide Prevention","scope_note":"Specific strategies for averting suicides. These include mental HEALTH PROMOTION and monitoring PSYCHOLOGICAL WELL-BEING and other intervention programs targeting susceptible individuals."},
{":id":"row-umvx~5m89~u6av",":version":"rv-23ux~5nm6_tuyg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I01","tree_category":"Social Sciences","mesh_heading":"Tobacco Control","scope_note":"Policies, regulations and programs implemented to encourage SMOKING PREVENTION and reduce TOBACCO USE DISORDER by various measures, e.g., TOBACCO INDUSTRY regulation, SMOKE-FREE POLICY and SMOKE CESSATION programs ."},
{":id":"row-ph4w_32qe-8dyw",":version":"rv-wt5v.ia8c.j6ij",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"I03","tree_category":"Human Activities","mesh_heading":"Wildlife Trade","scope_note":"Commerce of non-domesticated WILD ANIMALS or plants. Wildlife trade, particularly illegal trades, threaten ECOSYSTEMS and drives up SPECIES EXTINCTION. It also increases chance of emerging ZOONOSES."},
{":id":"row-mmn5_cvqv~6ygg",":version":"rv-v9kg~auut.9bhf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"J01","tree_category":"Technology, Industry, and Agriculture","mesh_heading":"Layer-by-Layer Nanoparticles","scope_note":"Nanostructures fabricated by assembly of ordered layers of known compositions primarily through electro-static interactions. Such nanoparticles can be used for targeted delivery of complex components in ordered release patterns."},
{":id":"row-4np6-xi97.f4kb",":version":"rv-vsmq~45tf_axd7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"J01","tree_category":"Technology, Industry, and Agriculture","mesh_heading":"Phytosomes","scope_note":"Lipid-based vesicular drug delivery systems that are structurally related to LIPOSOMES. Unlike LIPOSOMES, PHYTOSOMES have their active ingredient as a part of their lipid membrane itself."},
{":id":"row-dt8u.fwr8-jdck",":version":"rv-rnxr~is7w_yur7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"J02","tree_category":"Food and Beverages","mesh_heading":"Dietary Advanced Glycation End Products","scope_note":"Advanced glycation end products (AGEs) present in food. They are absorbed by the GASTROINTESTINAL SYSTEM and contribute to the body's total AGEs. The food BROWNING REACTION, such as occurs during food processing or cooking with high heat (frying, broiling, grilling, roasting, etc.) accelerates the formation of AGEs in food."},
{":id":"row-ccxr-m747_593m",":version":"rv-fqdg_2c39_v7qv",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"J02","tree_category":"Food and Beverages","mesh_heading":"Food, Processed","scope_note":"Any raw agricultural commodity that has been subject to washing, cleaning, milling, cutting, chopping, heating, pasteurizing, blanching, cooking, canning, freezing, drying, dehydrating, mixing, packaging or other procedures that alter the food from its natural state. (from  A Guide to Federal Terms and Acronyms. Lanham, MD: Government Institutes.1991)"},
{":id":"row-ppw7.6vgj_efai",":version":"rv-iwei-r9hh~xsqw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"K01","tree_category":"Humanities","mesh_heading":"Antiracism","scope_note":"Beliefs, actions or intentions, and policies that oppose RACISM or discrimination  based on RACE."},
{":id":"row-66k5_743v_maus",":version":"rv-2kng~e6as.jk2k",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"K01","tree_category":"Humanities","mesh_heading":"Psychological Well-Being","scope_note":"Condition of existence, or state of awareness, in which psychological needs are satisfied"},
{":id":"row-tqp9_pzpw-qxik",":version":"rv-rgvt~u7i5_vcns",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Case Reports as Topic","scope_note":"Clinical presentations that may be followed by evaluative studies that eventually lead to a diagnosis."},
{":id":"row-22fk~w3js_tvex",":version":"rv-tps7_73r3_jjyq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Information Sources","scope_note":"Various communications media, information centers, information services that are are utilized to obtain information."},
{":id":"row-r4e9_rpqf-k85a",":version":"rv-p89m_ucre.f9nx",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Motion Capture","scope_note":"Technological process of recording the MOTION and MOVEMENT of objects (e.g., surgical instrument in robotic surgery), body parts (e.g., EYE MOVEMENT), animals or people."},
{":id":"row-2r79-sh2u-jyen",":version":"rv-a46q.gt4u~94xa",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Multiomics","scope_note":"The study of a variety of omic data (TRANSCRIPTOME; PROTEOME; METABOLOME; etc.) generated from the same biological source such as a cell type or organ during normal versus diseased states."},
{":id":"row-gjhr-ww7s_knby",":version":"rv-d4bk~jikt.fbsz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Multiomics","scope_note":"The study of a variety of omic data (TRANSCRIPTOME; PROTEOME; METABOLOME; MICROBIOME, etc.) as the data set generated from the same biological source such as a cell type or organ during normal versus diseased states."},
{":id":"row-wy6q~vth9~zjfz",":version":"rv-j234_earp~98f9",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Random Forest","scope_note":"An algorithm used in decision analysis and MACHINE LEARNING that uses a set of trees to combine output of multiple, randomly generated DECISION TREES. The final class of each tree is aggregated and evaluated by weighted values to construct the final classifier."},
{":id":"row-bxwd~xwha-y5g9",":version":"rv-ysnh~5g88_z9wk",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Secondary Data Analysis","scope_note":"Analysis or reanalysis of existing data collected by someone else usually  for a different purpose."},
{":id":"row-2vix~pnkp~fqyp",":version":"rv-mecw~4ekj_6g9n",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"L01","tree_category":"Information Science","mesh_heading":"Volume Electron Microscopy","scope_note":"Electron microscopy techniques designed to reconstruct 3-D images at micrometer volume scales at nanometer (nm) level resolutions. Volume electron microscopy uses various techniques to render, segment and reconstruct 3-D images from stacked sequential 2-D images of incremental z-planes."},
{":id":"row-9smu.pw6m.ajv4",":version":"rv-3wgm.rru5_spjw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"African People","scope_note":"People native to or inhabitants of AFRICA."},
{":id":"row-wve7~cg6q.dvpk",":version":"rv-fyz5~gt4u-cnuk",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Asian American Native Hawaiian and Pacific Islander","scope_note":"Members of Asian American, Native Hawaiian, and Pacific Islander community."},
{":id":"row-b4c7_f3uj~6hrp",":version":"rv-wp9p-r8p4~z7p7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Australasian People","scope_note":"People native to or inhabitants of AUSTRALASIA including AUSTRALIA and NEW ZEALAND."},
{":id":"row-465z-tjrb-dqqf",":version":"rv-dqgg.ycbg-c2hz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Caribbean People","scope_note":"People native to or inhabitants of islands in the Caribbean Sea or CARIBBEAN including ANTIGUA AND BARBUDA; ARUBA; BAHAMAS; BARBADOS; BRITISH VIRGIN ISLANDS; CARIBBEAN NETHERLANDS; CUBA; CURACAO; DOMINICA; DOMINICAN REPUBLIC; GRENADA; GUADELOUPE; HAITI; JAMAICA; MARTINIQUE; PUERTO RICO; SAINT KITTS AND NEVIS; SAINT LUCIA; SAINT VINCENT AND THE GRENADINES; SINT MAARTEN; TRINIDAD AND TOBAGO; and UNITED STATES VIRGIN ISLANDS."},
{":id":"row-rm7y~csar-ubzk",":version":"rv-ecjk~mkyt_7uan",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Central African People","scope_note":"People native to or inhabitants of the CENTRAL AFRICA including CAMEROON; CENTRAL AFRICAN REPUBLIC; CHAD; CONGO; DEMOCRATIC REPUBLIC OF THE CONGO; EQUATORIAL GUINEA; GABON; and SAO TOME AND PRINCIPE. It includes indigenous peoples in the Congo Basin. Sometimes people native or inhabitants of the country of Central African Republic are referred to as Central Africans."},
{":id":"row-rx46~jh8s.dxbe",":version":"rv-3gff-3242_z7ss",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Central American People","scope_note":"People native to or inhabitants of CENTRAL AMERICA including BELIZE; COSTA RICA; EL SALVADOR; GUATEMALA; HONDURAS; NICARAGUA; and PANAMA."},
{":id":"row-44p9_dscq.fxpc",":version":"rv-sdnf~rdx4~kadp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Central Asian People","scope_note":"People native to or inhabitants of CENTRAL ASIA including KAZAKHSTAN; KYRGYZSTAN; TAJIKISTAN; TURKMENISTAN and UZBEKISTAN."},
{":id":"row-v4a4_fe5i_m6se",":version":"rv-ev75.f3kz_4uaz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Combat Medics","scope_note":"Individuals trained to provide medical care in a military operational or combat environment."},
{":id":"row-4ixu~94fb_j736",":version":"rv-jvdv~augn_864n",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Correctional Facilities Personnel","scope_note":"Persons who work at JAILS; PRISONS; or other CORRECTIONAL INSTITUTIONS."},
{":id":"row-hj6k-iqsq-rvtk",":version":"rv-3rkf-2mw4~mhjf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"East African People","scope_note":"People native to or inhabitants of EASTERN AFRICA including BURUNDI, DJIBOUTI, ERITREA, ETHIOPIA, KENYA, RWANDA, SOMALIA, SOUTH SUDAN, SUDAN, TANZANIA, and UGANDA and islands COMOROS; MADAGASCAR and SEYCHELLES."},
{":id":"row-pr2j~yzms_5ne4",":version":"rv-jmdb_4zzk~zg5p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"East Asian People"},
{":id":"row-4htr.3ubz~8h8p",":version":"rv-h8rb_mh2x_f4ga",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Eastern European People","scope_note":"People native to or inhabitants of EASTERN EUROPE including ALBANIA; BOSNIA AND HERZEGOVINA; BULGARIA; CROATIA; CZECH REPUBLIC; ESTONIA; HUNGARY; KOSOVO; LATVIA; LITHUANIA; MOLDOVA; MONTENEGRO; POLAND; REPUBLIC OF NORTH MACEDONIA; REPUBLIC OF BELARUS; ROMANIA; RUSSIA; SERBIA; SLOVAKIA; SLOVENIA; and UKRAINE."},
{":id":"row-fw5i~qxgr~i3pu",":version":"rv-7zre_cauq-wmuy",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"European People","scope_note":"People native to or inhabitants of EUROPE."},
{":id":"row-zp7e~3txt-fh28",":version":"rv-6ksb_ncnv.ua8i",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Gynecologists","scope_note":"Qualified medical professionals who specialize in GYNECOLOGY."},
{":id":"row-2hbq.vkbh_2utv",":version":"rv-5jiy.d98s~9rea",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Infant, Large for Gestational Age","scope_note":"Infants whose BIRTH WEIGHT is larger than the 90th percentile for a given gestational age."},
{":id":"row-6hfi_tj8g~q2mw",":version":"rv-skj4-m3gv-9isd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Middle Eastern and North Africans","scope_note":"People native to or inhabitants of the MIDDLE EAST and NORTH AFRICA."},
{":id":"row-74zq.4vrm-ppjj",":version":"rv-ij5v.gs8y.7z86",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Navajo People","scope_note":"Southern Athabaskan-speaking Native American people generally associated with the Southwestern states. Navajo Nation is the largest Native American territory in the United States."},
{":id":"row-nsfv_tmsn_v8zj",":version":"rv-pbwe~xbaw-7t3i",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"North African People","scope_note":"People native to or inhabitants of NORTH AFRICA including ALGERIA; EGYPT; LIBYA; MOROCCO; TUNISIA and the CANARY ISLANDS."},
{":id":"row-4b4n~9c29-2j3b",":version":"rv-vc67~w5p3.5fys",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"North American People","scope_note":"People native to or inhabitants of NORTH AMERICA."},
{":id":"row-5akh-bdp4-u2aa",":version":"rv-bcqv-v3tq.53mm",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"North Asian People","scope_note":"People native to or inhabitants of the NORTHERN ASIA including SIBERIA ."},
{":id":"row-qqxa~3c5b.hqda",":version":"rv-rzf9~8tpz.bh54",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Obstetricians","scope_note":"Qualified medical professionals who specialize in OBSTETRICS."},
{":id":"row-7ahh.hdzv-zbam",":version":"rv-yz9i-px4z.84dr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Oceanians","scope_note":"People native to or inhabitants of OCEANIA including MICRONESIA; MELANESIA; POLYNESIA; AUSTRALIA and NEW ZEALNAD."},
{":id":"row-zat5_w5ea-kwsp",":version":"rv-x8qz~ghch.a7re",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Pacific Island People","scope_note":"Persons having origins in any of PACIFIC ISLANDS. Note that OMB category NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER is available for United States population groups. Race and ethnicity terms, as used in the federal government, are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies."},
{":id":"row-w4r7-g3uy~nga9",":version":"rv-9agd~68hd-nakj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Paramedics","scope_note":"Health care workers who perform tasks which must otherwise be performed by a physician or other health professional, in a variety of clinical settings such as EMERGENCY MEDICAL SERVICES, ambulance services, hospitals and clinics as well as non-clinical roles, such as education, leadership, public health and research. Paramedics may practice under medical direction or independently, often in unscheduled, unpredictable or dynamic settings."},
{":id":"row-ksrn.kejn-wvgg",":version":"rv-u5eg.kns5_4e2p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Pima People","scope_note":"Oʼodham-speaking Native American people generally associated with Southwestern Arizona."},
{":id":"row-k7ak_8z7v_cig6",":version":"rv-tftd.wdts-3jkn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Population Groups, US","scope_note":"Individuals classified according US federal government used for US federal data on race and ethnicity. Race and ethnicity terms are self-identified social construct. MeSH may contain outdated and offensive population terms only to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies."},
{":id":"row-eq26~spny-3qka",":version":"rv-tqyg.nach~mhjz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Scandinavians and Nordic People","scope_note":"People native to or inhabitants of the SCANDINAVIAN AND NORDIC COUNTRIES."},
{":id":"row-7kkw~4mht-kmn4",":version":"rv-k46g.wf2a.edr3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"South American People","scope_note":"People native to or inhabitants of SOUTH AMERICA including ARGENTINA; BOLIVIA; BRAZIL; CHILE; COLOMBIA; ECUADOR; FRENCH GUIANA; GUYANA; PARAGUAY; PERU; SURINAME; URUGUAY; and VENEZUELA."},
{":id":"row-7n8i.taec_3new",":version":"rv-umcp_ahnc_y5h6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"South Asian People","scope_note":"People native to or inhabitants of SOUTHERN ASIA including AFGHANISTAN; BANGLADESH; BHUTAN; INDIA; MALDIVES; NEPAL; PAKISTAN and SRI LANKA. It includes people native or inhabitants of MEKONG VALLEY."},
{":id":"row-jan3~p8qd-8fw6",":version":"rv-f4xg~xj6s_abhr",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Southeast Asian People"},
{":id":"row-w66e.nky2.7giq",":version":"rv-5zw2.8g8c.bss7",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Southern African People","scope_note":"People native to or inhabitants of SOUTHERN AFRICA including ANGOLA; BOTSWANA; EWATINI; LESOTHO; MALAWI; MOZAMBIQUE; NAMIBIA; SOUTH AFRICA; ZAMBIA; and ZIMBABWE."},
{":id":"row-wbgm_hkqj-iah9",":version":"rv-xp3g_2n87~kr5q",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Sub-Saharan African People","scope_note":"People native to or inhabitants of SUB-SAHARAN AFRICA including ANGOLA; BENIN; BOTSWANA; BURKINA FASO; BURUNDI; CABO VERDE; CAMEROON; CENTRAL AFRICAN REPUBLIC; CHAD; CONGO; COTE D'IVOIRE; DEMOCRATIC REPUBLIC OF THE CONGO; DJIBOUTI; EQUATORIAL GUINEA; ERITREA; ESWATINI; ETHIOPIA; GABON; GAMBIA; GHANA; GUINEA; GUINEA-BISSAU; KENYA; LESOTHO; LIBERIA; MALAWI; MALI; MAURITANIA; MOZAMBIQUE; NAMIBIA; NIGER; NIGERIA; RWANDA; SAO TOME AND PRINCIPE; SENEGAL; SIERRA LEONE; SOMALIA; SOUTH AFRICA; SOUTH SUDAN; SUDAN; TANZANIA; TOGO; UGANDA; ZAMBIA; and ZIMBABWE."},
{":id":"row-fhui-f6gj_2em2",":version":"rv-pi6w-msrp_4jen",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"Traditional Medicine Practitioners","scope_note":"Health personnel using systems of medicine based on cultural beliefs and practices handed down from generation to generation, including mystical and magical rituals (SPIRITUAL THERAPIES); TRADITIONAL MEDICINE; PHYTOTHERAPY; HERBAL MEDICINE; and other treatments which may not be explained by modern medicine."},
{":id":"row-wcdr-f59w-t7v9",":version":"rv-4yu3.9zw7~kcxg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"West African People","scope_note":"People native to or inhabitants of WEST AFRICA (western part of the sub-Saharan Africa) including BENIN; BURKINA FASO; CABO VERDE; IVORY COAST; GAMBIA; GHANA; GUINEA; GUINEA-BISSAU; LIBERIA; MALI; MAURITANIA; NIGER; NIGERIA; SENEGAL; SIERRA LEONE; TOGO and CAPE VERDE ISLANDS."},
{":id":"row-re4d_yvxm-atac",":version":"rv-u39m.eq8a_8fwk",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"West Asian People","scope_note":"People native to or inhabitants of WESTERN ASIA including BANGLADESH; BHUTAN; INDIA; IRAN; IRAQ; ISRAEL; JORDAN; KUWAIT; LEBANON; MALDIVES; NEPAL; OMAN; PALESTINIAN TERRITORIES; PAKISTAN; QATAR; SAUIDI ARABIA; SRI LANKA; SYRIA; TURKEY; UNITED ARAB EMIRATES and YEMEN."},
{":id":"row-4776_eugw.x4ee",":version":"rv-p5r8.gq79-5cs8",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"M01","tree_category":"Persons","mesh_heading":"White","scope_note":"A person having origins in any of the white racial groups of Europe, the Middle East and North Africa (https://www.federalregister.gov/documents/1997/10/30/97-28653/revisions-to-the-standards-for-the classification-of-federal-data-on-race-and-ethnicity). In the United States it is used for classification of federal government data on race and ethnicity. Race and ethnicity terms are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies."},
{":id":"row-bh8k_79ue~9nj9",":version":"rv-sbun_7t7r.i2n6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N01","tree_category":"Population Characteristics","mesh_heading":"Collective Efficacy","scope_note":"A group belief and perception in its ability to complete a task successfully. It includes shared belief it can control deviant behavior of a member."},
{":id":"row-jaux~wdcg~xtbc",":version":"rv-dsjp_qvdj.swgu",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N01","tree_category":"Population Characteristics","mesh_heading":"Extended Family","scope_note":"A household with members of at least three generations."},
{":id":"row-nj78.uxsr-v36z",":version":"rv-gsbb_y25s~ywd2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N01","tree_category":"Population Characteristics","mesh_heading":"Family Structure","scope_note":"Structural nature of relationships among members of a household typically in reference to a MINOR residing in the same home. More broadly any organizational framework that determines family membership, and the functions and hierarchical position of family members (https://eric.ed.gov/?qt=Family+Structure&ti=Family+Structure)."},
{":id":"row-vmaa_fgya_hiz5",":version":"rv-heaz.9qq2~c4fn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N01","tree_category":"Population Characteristics","mesh_heading":"Low Socioeconomic Status","scope_note":"Socioeconomic status with relatively low income and/or assets (POVERTY) and EDUCATIONAL LEVEL."},
{":id":"row-8a6i.tv5g.5uhu",":version":"rv-nzba_2zdu-sjkp",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N01","tree_category":"Population Characteristics","mesh_heading":"Residential Segregation","scope_note":"Spatial separation of HOUSING within a geographic area based on racial, ethnic, nationality and other SOCIOECONOMIC FACTORS."},
{":id":"row-qzsn~rghu~qiza",":version":"rv-a665~jsae-2dqk",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N01","tree_category":"Population Characteristics","mesh_heading":"Working Conditions","scope_note":"Conditions of a WORKPLACE such as weather (e.g., indoor or outdoor), safety (e.g., exposure to hazardous materials), environment and workplace culture and management style."},
{":id":"row-uu85.hr6s~ya9a",":version":"rv-k7xv_6nbk.xdzz",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Blood Banking","scope_note":"The administrative procedures and methods required for collecting, characterizing and storing blood or plasma in BLOOD BANKS."},
{":id":"row-8buw.bwi5_y3yn",":version":"rv-25zk~ac8f_s2ht",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Blood Donation","scope_note":"Voluntary giving of BLOOD."},
{":id":"row-5tay_82kt_gzui",":version":"rv-cemw_9k5x-yx9p",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Cognitive Training","scope_note":"A non-pharmacological form of treatment focusing on guided practice on tasks that target specific cognitive functions. These functions include memory, attention, and problem-solving. (from Cochrane.org/CD013069/DEMENTIA_cognitive-training-people-mild-moderate-dementia)"},
{":id":"row-2yrh_5hi5_dxar",":version":"rv-qrm5~5nat-qp6s",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Combat Medics","scope_note":"Individuals trained to provide medical care in a military operational or combat environment."},
{":id":"row-8jdt.s5z3_bdgp",":version":"rv-jkfw.hjpc~e3pt",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Gynecologists","scope_note":"Qualified medical professionals who specialize in GYNECOLOGY."},
{":id":"row-8jya.t2nd_sp7u",":version":"rv-iq7u.nfkz.hhat",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Obstetricians","scope_note":"Qualified medical professionals who specialize in OBSTETRICS."},
{":id":"row-s4aa.ftjp.k9qu",":version":"rv-hk8q-3k3n.yhwt",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Paramedics","scope_note":"Health care workers who perform tasks which must otherwise be performed by a physician or other health professional, in a variety of clinical settings such as EMERGENCY MEDICAL SERVICES, ambulance services, hospitals and clinics as well as non-clinical roles, such as education, leadership, public health and research. Paramedics may practice under medical direction or independently, often in unscheduled, unpredictable or dynamic settings."},
{":id":"row-qh8k~5iha-f6x3",":version":"rv-vcgw~22xp_2qg3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Suicide Prevention","scope_note":"Specific strategies for averting suicides. These include mental HEALTH PROMOTION and monitoring PSYCHOLOGICAL WELL-BEING and other intervention programs targeting susceptible individuals."},
{":id":"row-7bsm.hwew-7d66",":version":"rv-ug4p-p65b_r4vn",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N02","tree_category":"Health Care Facilities, Manpower, and Services","mesh_heading":"Traditional Medicine Practitioners","scope_note":"Health personnel using systems of medicine based on cultural beliefs and practices handed down from generation to generation, including mystical and magical rituals (SPIRITUAL THERAPIES); TRADITIONAL MEDICINE; PHYTOTHERAPY; HERBAL MEDICINE; and other treatments which may not be explained by modern medicine."},
{":id":"row-vbzb~faaq_zec2",":version":"rv-kk4b.s5e2_esbd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Antiracism","scope_note":"Beliefs, actions or intentions, and policies that oppose RACISM or discrimination  based on RACE."},
{":id":"row-g5u3-q7hc~xzfi",":version":"rv-8arw_t8nz~reer",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Collective Efficacy","scope_note":"A group belief and perception in its ability to complete a task successfully. It includes shared belief it can control deviant behavior of a member."},
{":id":"row-y2ku.h284-awza",":version":"rv-a8hw.wgdn_m344",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Cost-Effectiveness Analysis","scope_note":"A method of comparing the cost of a program with its expected outcomes that are qualitative in nature. Cost effectiveness compares alternative ways to achieve a specific set of results."},
{":id":"row-wvpv-xc7r_6v5w",":version":"rv-jh3s~t2rs~hi7j",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Evidence Gaps","scope_note":"Areas where little or no evidence from impact evaluations and SYSTEMATIC REVIEWS is available and where future research should be focused (from https://openknowledge.worldbank.org/handle/10986/16941)."},
{":id":"row-kjbm.hmcx~sx6k",":version":"rv-xn5p.3t22_4ccb",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Resource-Limited Settings","scope_note":"Environments with barriers to quality critical care characterized by lack of epidemiological data and context-specific evidence for medical decision-making, deficiencies in health systems organization and resources, and institutional obstacles to implementation of life-saving interventions."},
{":id":"row-3z36~vu86_3uh2",":version":"rv-dudn-bd2k_5hnh",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Social Group","scope_note":"A collection of two or more people who share a common identity as defined by beliefs, codes of conduct, CULTURE and SOCIAL NORMS."},
{":id":"row-47fd.xii6-wj3d",":version":"rv-5gyg_6qnx.rnzg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N03","tree_category":"Health Care Economics and Organizations","mesh_heading":"Tobacco Control","scope_note":"Policies, regulations and programs implemented to encourage SMOKING PREVENTION and reduce TOBACCO USE DISORDER by various measures, e.g., TOBACCO INDUSTRY regulation, SMOKE-FREE POLICY and SMOKE CESSATION programs ."},
{":id":"row-mh2r.avi4~nb4e",":version":"rv-i9fd.jhxq_7ia4",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N04","tree_category":"Health Services Administration","mesh_heading":"Access to Primary Care","scope_note":"The degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive PRIMARY CARE."},
{":id":"row-kbnf_dwdk~iszz",":version":"rv-j4eb-6gts-9vaf",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N04","tree_category":"Health Services Administration","mesh_heading":"Clinical Relevance","scope_note":"Criteria to determine whether a finding (e.g., clinical examination, lab test, imaging results) requires a medical intervention for meaningful improvement in outcome often to avoid OVERDIAGNOSIS and/or OVERTREATMENT."},
{":id":"row-ua4t~n39r~jh2i",":version":"rv-ajfa.tya5.vuvq",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N04","tree_category":"Health Services Administration","mesh_heading":"Dental Care Team","scope_note":"Care of dental patients by a multidisciplinary team usually organized under the leadership of a dentist; each member of the team has specific responsibilities and the whole team contributes to the oral care of the patient."},
{":id":"row-kkex.vuyy_k9mz",":version":"rv-ug7j_ryhc.u8yg",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N04","tree_category":"Health Services Administration","mesh_heading":"Rapid Diagnostic Tests","scope_note":"Diagnostic assays designed for use at the point-of-care (POC) that can be adapted for use in low-resource settings. These tests are low-cost, simple to operate and read, sensitive, specific, stable at high temperatures, and works in a short period of time."},
{":id":"row-3437.ntd2_dei9",":version":"rv-awwj_uwen.jz8f",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N04","tree_category":"Health Services Administration","mesh_heading":"Value-Based Health Care","scope_note":"Health system model designed to maximize value for patients. Value based healthcare often emphasizes better patient outcomes for healthcare cost through best practices (e.g., preventive screening, quality incentives)."},
{":id":"row-aevr-6tcs~a539",":version":"rv-xdgi-sf2h_kp3s",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N04","tree_category":"Health Services Administration","mesh_heading":"Working Conditions","scope_note":"Conditions of a WORKPLACE such as weather (e.g., indoor or outdoor), safety (e.g., exposure to hazardous materials), environment and workplace culture and management style."},
{":id":"row-vjdr~wrk5-mjcj",":version":"rv-w639_trbm_fz43",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Access to Primary Care","scope_note":"The degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive PRIMARY CARE."},
{":id":"row-tza3.ru99.7uvs",":version":"rv-bg47~rgc6.rrnj",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Antiracism","scope_note":"Beliefs, actions or intentions, and policies that oppose RACISM or discrimination  based on RACE."},
{":id":"row-6jhi~2xth.68sc",":version":"rv-73wh~ci3w-bihy",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Clinical Relevance","scope_note":"Criteria to determine whether a finding (e.g., clinical examination, lab test, imaging results) requires a medical intervention for meaningful improvement in outcome often to avoid OVERDIAGNOSIS and/or OVERTREATMENT."},
{":id":"row-nen6.c7wh~4y6u",":version":"rv-qyq4-pgs6_jum2",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Evidence Gaps","scope_note":"Areas where little or no evidence from impact evaluations and SYSTEMATIC REVIEWS is available and where future research should be focused (from https://openknowledge.worldbank.org/handle/10986/16941)."},
{":id":"row-a93b_8n7b-r6c9",":version":"rv-yigm-ai7w.b3qi",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Obesity Paradox","scope_note":"An observation that high BODY MASS INDEX is sometimes associated with lower CARDIOVASCULAR DISEASE mortality in certain population, e.g., ELDERLY."},
{":id":"row-7j8i-w8mg.8fxf",":version":"rv-swgp.k4t6~njjw",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Resource-Limited Settings","scope_note":"Environments with barriers to quality critical care characterized by lack of epidemiological data and context-specific evidence for medical decision-making, deficiencies in health systems organization and resources, and institutional obstacles to implementation of life-saving interventions."},
{":id":"row-bbfe.46gv_tqg5",":version":"rv-kqbm-ut9r~6wp6",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Secondary Data Analysis","scope_note":"Analysis or reanalysis of existing data collected by someone else usually  for a different purpose."},
{":id":"row-kp4r~9z9h~d5fp",":version":"rv-nt77-enus~buxh",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N05","tree_category":"Health Care Quality, Access, and Evaluation","mesh_heading":"Value-Based Health Care","scope_note":"Health system model designed to maximize value for patients. Value based healthcare often emphasizes better patient outcomes for healthcare cost through best practices (e.g., preventive screening, quality incentives)."},
{":id":"row-jz4b-ffnj~drdc",":version":"rv-gukt_zmq7_dcdd",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Collective Efficacy","scope_note":"A group belief and perception in its ability to complete a task successfully. It includes shared belief it can control deviant behavior of a member."},
{":id":"row-a882.z97r~9gk2",":version":"rv-3dfa.z7wb-2rwa",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Extended Family","scope_note":"A household with members of at least three generations."},
{":id":"row-uqj6-5qfm_cm9d",":version":"rv-i98q-puhw~5x4z",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Family Structure","scope_note":"Structural nature of relationships among members of a household typically in reference to a MINOR residing in the same home. More broadly any organizational framework that determines family membership, and the functions and hierarchical position of family members (https://eric.ed.gov/?qt=Family+Structure&ti=Family+Structure)."},
{":id":"row-gn3s_ajnx_at9b",":version":"rv-hdc4_qkxp-52qc",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Obesity Paradox","scope_note":"An observation that high BODY MASS INDEX is sometimes associated with lower CARDIOVASCULAR DISEASE mortality in certain population, e.g., ELDERLY."},
{":id":"row-kmwe-3qpr_767g",":version":"rv-h8my.fest-spey",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Psychological Well-Being","scope_note":"Condition of existence, or state of awareness, in which psychological needs are satisfied"},
{":id":"row-serq_anm7.5pyj",":version":"rv-7xxj-m7pt-zgwk",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Residential Segregation","scope_note":"Spatial separation of HOUSING within a geographic area based on racial, ethnic, nationality and other SOCIOECONOMIC FACTORS."},
{":id":"row-5xg4-4qn6-8r5p",":version":"rv-mq7v~ve34.6t63",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"N06","tree_category":"Environment and Public Health","mesh_heading":"Secondary Data Analysis","scope_note":"Analysis or reanalysis of existing data collected by someone else usually  for a different purpose."},
{":id":"row-uysw~6zri~kqrn",":version":"rv-456n-7vs3.eed3",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"Z01","tree_category":"Geographic Locations","mesh_heading":"Asia, Southern","scope_note":"The geographical designation for the countries of AFGHABUISTAN; BANGLADESH; BHUTAN; INDIA; MALDIVES; NEPAL; PAKISTAN; and SRI LANKA."},
{":id":"row-85s2-wmpj~mxe4",":version":"rv-b8ic.n5ua-44nt",":created_at":"2022-12-19T22:06:20.900Z",":updated_at":"2022-12-19T22:06:20.900Z","mn":"Z01","tree_category":"Geographic Locations","mesh_heading":"Maldives","scope_note":"Country in southern Asia, an island in the Indian Ocean. The capital is city of Male."}
]