MedGen is NCBI's portal to information about conditions and phenotypes related to Medical Genetics. Terms from the NIH Genetic Testing Registry (GTR), UMLS, HPO, Orphanet, ClinVar and other sources are aggregated into concepts, each of which is assigned a unique identifier and a preferred name and symbol. The core content of the record may include names, identifiers used by other databases, mode of inheritance, clinical features, and map location of the loci affecting the disorder. The concept identifier (CUI) is used to aggregate information about that concept, similar to the way NCBI Gene serves as a gateway to gene-related information.
MedGen provides links to such resources as: Genetic tests registered in the NIH Genetic Testing Registry (GTR), GeneReviews, ClinVar, OMIM, Related genes, Disorders with similar clinical features, Medical and research literature, Practice guidelines, Consumer resources, Ontologies such as HPO and ORDO.
Links to the GTR, GeneReviews, and Practice Guidelines are based on curation by NCBI staff. Other data feeds are automated, but reviewed by NCBI staff and informed by feedback from the community.
Medical Subject Headings (MeSH) is a hierarchically-organized terminology for indexing and cataloging of biomedical information. It is used for the indexing of PubMed and other NLM databases. Please see the Terms and Conditions for more information regarding the use and re-use of MeSH. NLM produces Medical Subject Headings XML, ASCII, MARC 21 and RDF formats.
Updates to the data files are made according to the following schedule:
The MEDLINE/PubMed Baseline Repository (MBR) provides access to each MEDLINE/PubMed Baseline snapshot starting with the 2002 MEDLINE Baseline. Each baseline contains a snapshot of MEDLINE citations in the state they were at a given moment in time without the MeSH vocabulary updates and other revisions that occur during the year. The baseline snapshot is created at the beginning of each new MeSH Indexing Year. The records included in the MEDLINE/PubMed Baseline databases represent a static view of the data at the time each baseline database was created.
NLM produces a baseline set of MEDLINE/PubMed citation records in XML format in December of each year. NLM also produces daily update files that include new, revised and deleted citations. Downloading data from the National Library of Medicine FTP servers indicates your acceptance of the following Terms and Conditions: No charges, usage fees or royalties are paid to NLM for this data. https://www.nlm.nih.gov/databases/download/terms_and_conditions_pubmed.html
MedlinePlus is the National Institutes of Health's Web site for patients and their families and friends. Produced by the National Library of Medicine, the world’s largest medical library, it brings you information about diseases, conditions, and wellness issues in language you can understand. MedlinePlus offers reliable, up-to-date health information, anytime, anywhere, for free.
MedPix is a database of patient cases integrating images and textual information. The content material is organized by disease location (organ system), pathology category, patient profiles, and by image classification and caption.
MeSH on Demand identifies MeSH Terms in your text using the NLM Medical Text Indexer (MTI) program. After processing, MeSH on Demand returns a list of MeSH Terms relevant to your text as well as a list of related articles from PubMed.
MetaMap is a highly configurable application developed by the Lister Hill National Center for Biomedical Communications at the National Library of Medicine (NLM) to map biomedical text to the UMLS Metathesaurus or, equivalently, to identify Metathesaurus concepts referred to in English text. MetaMap employs a knowledge-intensive approach, natural-language processing (NLP), and computational-linguistic techniques, and is used worldwide in industry and academia. At NLM, MetaMap is one of the foundations of NLM's Medical Text Indexer (MTI), which is applied to both semiautomatic and fully automatic indexing of biomedical literature. Technical documentation at http://metamap.nlm.nih.gov/#Downloads
An interactive Web application that enables users to visualize multiple alignments created by database search results or other software applications. The MSA Viewer allows users to upload an alignment and set a master sequence and to explore the data using features such as zooming and changing of coloration.