BLAST finds regions of similarity between biological sequences.

BLAST includes several specialized search interfaces: SmartBLAST, Primer-BLAST, Global Align, CD-Search, IgBLAST, VecScreen, CDART, Multiple Alignment, MOLE-BLAST, Searches at a Cloud Provider, BLAST+ Docker Image

The BioProject database links to data that have been or will be deposited into archival databases maintained at members of the International Nucleotide Sequence Database Consortium (INSDC, which comprises the DNA DataBank of Japan (DDBJ), the European Nucleotide Archive at European Molecular Biology Laboratory (ENA), and GenBank at the National Center for Biotechnology Information (NCBI)).

The BioSample database contains descriptions of biological source materials used in experimental assays.

A collection of online books and documents in life science and healthcare whose full text can be searched through the Entrez system. Bookshelf provides free online access to books and documents in life science and healthcare.

CDTree is a stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies, and also allows users to create their own.

ClinVar aggregates information about genomic variation and its relationship to human health.

A stand-alone application for viewing 3-dimensional structures from NCBI Entrez retrieval service. Runs on Windows, Macintosh, and UNIX and can be configured to receive data from most popular Web browsers.

COBALT is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and sequence similarity, using RPS-BLAST, BLASTP, and PHI-BLAST.

Coffee Break is a resource at NCBI that combines reports on recent biomedical discoveries with use of NCBI tools. The result is an interactive tutorial that tells a biological story. Each report is based on a discovery reported in one or more articles from the recently published peer-reviewed literature. After a brief introduction that sets the work described into a broader context, the report focuses on how a molecular understanding can provide explanations of observed biology and lead to therapies for diseases.

The Consensus CDS (CCDS) project is a collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated and of high quality. The long term goal is to support convergence towards a standard set of gene annotations.

Available information includes: Announcements, Overview, Access and Availability, Collaborators, CCDS Identifiers and Tracking, Process Flow and Quality Testing, Publications.

Initial results from the Consensus CDS project are now available from the participants' genome browser Web sites. In addition, CCDS identifiers are indicated on the relevant NCBI RefSeq and Entrez Gene records. CCDS reports can be accessed by following provided links, or by directly querying the underlying database using the query interface provided at the top of the home page. The CCDS dataset is also available for anonymous FTP.