The CCRIS database contains chemical records with carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition test results. It was developed by the National Cancer Institute (NCI). Data are derived from studies cited in primary journals, current awareness tools, NCI reports, and other sources. Test results have been reviewed by experts in carcinogenesis and mutagenesis. CCRIS provides historical information from the years 1985 - 2011. It is no longer updated.

Enables first responders and other healthcare providers and planners to plan for, respond to, recover from, and mitigate the effects of mass-casualty incidents involving accidental or terrorist chemical releases.

ChemIDplus is no longer updated. These are the final files from February 22, 2023. All ChemIDplus data have been incorporated into PubChem.

ChemIDplus was a dictionary of over 400,000 chemicals (names, synonyms, and structures). ChemIDplus includes links to NLM and other databases and resources, including links to federal, state and international agencies. NLM makes a subset of ChemIDplus data available for download. The ChemIDplus Subset does not include the structure or the toxicity data available from the NLM web versions of the database. The ChemIDplus Subset is updated monthly.

***The Computational Photography Project for Pill Identification (C3PI) was discontinued in 2018. No new images will be added to the collection. Identifiers for pills will not be updated.***

The Computational Photography Project for Pill Identification (C3PI) created the RxIMAGE database of freely available high-quality digital images of prescription pills and associated data for use in conducting computer vision research in text- and image-based search and retrieval. Photographs of pills for the RxIMAGE database were taken under laboratory lighting conditions, from a camera directly above the front and the back faces of the pill, at high resolution, and using specialized digital macro-photography techniques. Image segmentation algorithms were then applied to create the JPEG images in the database.

Historical information about the project is available in the NLM archive at https://wayback.archive-it.org/7867/20190423182937/https:/lhncbc.nlm.nih.gov/project/c3pi-computational-photography-project-pill-identification.

HSDB was a toxicology database that focused on the toxicology of potentially hazardous chemicals. It provided information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, nanomaterials, and related areas. The information in HSDB has been assessed by a Scientific Review Panel.

This version of HSDB data includes a subset of HSDB for downloading, but is no longer updated. HSDB data has been incorporated into PubChem.

Provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements.

This resource was retired on January 28, 2021 and is no longer updated. These data remain available to support research and development efforts. Pillbox's final image library is available at https://ftp.nlm.nih.gov/projects/pillbox/pillbox_production_images_full_202008.zip. For more information on Pillbox's retirement visit https://www.nlm.nih.gov/pubs/techbull/ja20/ja20_pillbox_discontinue.html.

Pillbox contains metadata for oral solid dosage form medications, derived from FDA drug labeling, including physical characteristics, active and inactive ingredients, National Drug Codes, information about firms marketing those products, selected information from RxNorm, and links to images provided by the National Library of Medicine.

PubChem contains the chemical structures of small organic molecules and information on their biological activities. PubChem includes substance information, compound structures, and bioactivity data in three primary databases, PCSubstance, PCCompound, and PCBioAssay, respectively. PubChem is integrated with Entrez, NCBI's primary search engine, and also provides compound neighboring, sub/superstructure, similarity structure, bioactivity data, and other searching features. Technical documentation at http://pubchem.ncbi.nlm.nih.gov/help.html#faq

The RxClass Browser is a web application for exploring and navigating through the class hierarchies to find the RxNorm drug members associated with each class.

RxClass links drug classes of several drug sources including ATC, MeSH, NDF-RT and FDA/SPL to their RxNorm drug members (ingredients, precise ingredients and multiple ingredients).

RxClass allows users to search by class name or identifier to find the RxNorm drug members or, conversely, search by RxNorm drug name or identifier to find the classes that the RxNorm drug is a member of.

An interface for building applications that allows users to combine functions of various NLM drug APIs, including the RxNorm, RxClass, RxTerms, and NDF-RT APIs. Sequences of functions can be executed interactively or in batch mode.