The BioProject database links to data that have been or will be deposited into archival databases maintained at members of the International Nucleotide Sequence Database Consortium (INSDC, which comprises the DNA DataBank of Japan (DDBJ), the European Nucleotide Archive at European Molecular Biology Laboratory (ENA), and GenBank at the National Center for Biotechnology Information (NCBI)).

The BioSample database contains descriptions of biological source materials used in experimental assays.

BLAST (Basic Local Alignment Search Tool) finds regions of similarity between biological sequences.

BLAST includes several specialized search interfaces: SmartBLAST, Primer-BLAST, Global Align, CD-Search, IgBLAST, VecScreen, CDART, Multiple Alignment, MOLE-BLAST, Searches at a Cloud Provider, BLAST+ Docker Image

Identifies the conserved domains present in a protein sequence. CD-Search uses RPS-BLAST (Reverse Position-Specific BLAST) to compare a query sequence against position-specific score matrices that have been prepared from conserved domain alignments present in the Conserved Domain Database (CDD).

CDTree is a stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies, and also allows users to create their own.

ClinVar aggregates information about genomic variation and its relationship to human health.

The Consensus CDS (CCDS) project is a collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated and of high quality. The long term goal is to support convergence towards a standard set of gene annotations.

Conserved Domain Database (CDD) is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins.

Constraint-Based Multiple Alignment Tool (COBALT) is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and sequence similarity, using RPS-BLAST, BLASTP, and PHI-BLAST.

Database of Genomic Structural Variation (dbVar) is NCBI's database of human genomic Structural Variation — large variants >50 bp including insertions, deletions, duplications, inversions, mobile elements, translocations, and complex variants.