Supports finding human phenotype/genotype relationships with queries by phenotype, chromosome location, gene, and SNP identifiers. Currently includes information from dbGaP, the National Human Genome Research Institute (NHGRI) genome-wide association study (GWAS) Catalog, and Genotype - Tissue Expression (GTeX).

The PopSet database is a collection of related DNA sequences derived from population, phylogenetic, mutation and ecosystem studies that have been submitted to GenBank.

A utility for computing alignment of proteins to genomic nucleotide sequence based on a variation of the Needleman Wunsch global alignment algorithm and specifically accounts for introns and splice signals.

The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.

A collection of Reference Sequence (RefSeq) proteins, from the complete genomes of prokaryotes, plasmids, and organelles, that have been grouped and annotated based on sequence similarity and protein function.

Users can display, sort, subset and download position-specific score matrices (PSSMs) either from CDD records or from Position Specific Iterated (PSI)-BLAST protein searches.

PUG provides access to PubChem services via a programmatic interface. Users may download data, initiate chemical structure searches, standardize chemical structures and interact with E-utilities. Access PUG with standard URLs or via SOAP. Technical documentation at http://pubchem.ncbi.nlm.nih.gov/pug/pughelp.html

A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

Information about retroviruses and specialized tools for the analysis of retroviral proteins and genomes. The tools on this page aid in the identification, study and analysis of retroviral genomes and proteins. For instance, the HIV, human interaction database catalogs and organizes published data in peer-reviewed journals regarding HIV-1 and human protein interactions. Several links external to NCBI are also included for the purposes of education, research and health-related matters. These include links to the CDC, the Retroviruses textbook and other informative sites.

The Sequence Read Archive (SRA) stores sequencing data from the next generation of sequencing platforms including Roche 454 GS System®, Illumina Genome Analyzer®, Life Technologies AB SOLiD System®, Helicos Biosciences Heliscope®, Complete Genomics®, and Pacific Biosciences SMRT®.