Identifies the conserved domains present in a protein sequence. CD-Search uses RPS-BLAST (Reverse Position-Specific BLAST) to compare a query sequence against position-specific score matrices that have been prepared from conserved domain alignments present in the Conserved Domain Database (CDD).
The SKR Project was initiated at NLM in order to develop programs to provide usable semantic representation of biomedical free text by building on resources currently available at the library. The SKR project is concerned with reliable and effective management of the information encoded in natural language texts. The project develops programs that provide usable semantic representation of biomedical text by building on resources currently available at the Library, especially the UMLS knowledge sources and the natural language processing tools provided by the SPECIALIST system. This Java-based API to the Semantic Knowledge Representation (SKR) Scheduler facility was created to provide users with the ability to programmatically submit jobs to the Scheduler Batch and Interactive facilities instead of using the Web-based interface.
Images from the History of Medicine (IHM) in NLM Digital Collections provides online access to images from the historical collections of the U.S. National Library of Medicine. IHM includes image files of a wide variety of visual media including fine art, photographs, engravings, and posters that illustrate the social and historical aspects of medicine dating from the 15th to 21st century.
Supports finding human phenotype/genotype relationships with queries by phenotype, chromosome location, gene, and SNP identifiers. Currently includes information from dbGaP, the National Human Genome Research Institute (NHGRI) genome-wide association study (GWAS) Catalog, and Genotype - Tissue Expression (GTeX).
XML-encoded transcriptions and images of 828 handwritten letters (1786-1907) from the History of Medicine's Henkel Family correspondence collection; comprised largely of letters to and from Caspar C. Henkel (1835-1908).