TOXLINE was the National Library of Medicine (NLM) bibliographic database for toxicology, a varied science encompassing many disciplines. TOXLINE records provide bibliographic information covering the biochemical, pharmacological, physiological, and toxicological effects of drugs and other chemicals. TOXLINE references were drawn from various sources organized into component subfiles.
This version of TOXLINE is no longer updated. Updated TOXLINE content is available in PubMed or by searching PubMed using the search string: tox [sb] .
PubChem contains the chemical structures of small organic molecules and information on their biological activities. PubChem includes substance information, compound structures, and bioactivity data in three primary databases, PCSubstance, PCCompound, and PCBioAssay, respectively. PubChem is integrated with Entrez, NCBI's primary search engine, and also provides compound neighboring, sub/superstructure, similarity structure, bioactivity data, and other searching features. Technical documentation at http://pubchem.ncbi.nlm.nih.gov/help.html#faq
Provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements.
GEO is a public functional genomics data repository supporting MIAME-compliant data submissions. There are also tools provided to help users query and download experiments and curated gene expression profiles.
RxNorm provides normalized names for clinical drugs and links its names to many of the drug vocabularies commonly used in pharmacy management and drug interaction software, including those of First Databank, Micromedex, Gold Standard, and Multum. By providing links between these vocabularies, RxNorm can mediate messages between systems not using the same software and vocabulary.
Clinical Table Search Service (formerly "lforms-service") is a web service which software programs can use for querying clinical data tables. The API for each table is designed to work with our form field autocompletion package, but can be used by other programs as well. The tables may also be accessed through FHIR APIs. The FAQ page (https://clinicaltables.nlm.nih.gov/faq.html) has further details on terms of service, etc
The Meeting Abstracts database contains selected abstracts from meetings and conferences in the subject areas of: AIDS, Health Services Research, and Space Life Sciences, published between 1990 – 2010. The abstracts are organized into three collections, each available in XML file format. This dataset is no-longer updated.
MedPix is a database of patient cases integrating images and textual information. The content material is organized by disease location (organ system), pathology category, patient profiles, and by image classification and caption. Additional information at https://medpix.nlm.nih.gov/home
dbSNP contains human single nucleotide variations, microsatellites, and small-scale insertions and deletions along with publication, population frequency, molecular consequence, and genomic and RefSeq mapping information for both common variations and clinical mutations. dbSNP tutorials can be found at https://github.com/ncbi/dbsnp/tree/master/tutorials
Medical Subject Headings (MeSH) is a hierarchically-organized terminology for indexing and cataloging of biomedical information. It is used for the indexing of PubMed and other NLM databases. Please see the Terms and Conditions for more information regarding the use and re-use of MeSH. NLM produces Medical Subject Headings XML, ASCII, MARC 21 and RDF formats.
Updates to the data files are made according to the following schedule: