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Molecular biology/Genetics
External Link
Explore characteristics of amino acids by comparing their structural and chemical properties, predicting protein sequence changes caused by mutations, viewing common substitutions, and browsing functions of given residues in conserved domains.
Tags biochemistry protein tools & utilities
Updated
September 30 2022
Views
4,410

Molecular biology/Genetics
External Link
BLAST finds regions of similarity between biological sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance. Technical documentation at http://blast.ncbi.nlm.nih.gov/Blast.cgi?CMD=Web&PAGE_TYPE=BlastDocs
Tags api biochemistry biotechnology computational biology tools & utilities and 2 more
Updated
December 7 2022
Views
4,492

Molecular biology/Genetics
External Link
This resource provides cytogenetic locations for features or sequence locations, or sequence locations for cytogenetic locations.
Tags cytogenetics genomics tools & utilities
Updated
September 30 2022
Views
4,135

Molecular biology/Genetics
External Link
A stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies, and also allows users to create their own.
Tags dataset protein tools & utilities
Updated
September 30 2022
Views
2,512

Research
External Link
A stand-alone application for viewing 3-dimensional structures from NCBI Entrez retrieval service. Runs on Windows, Macintosh, and UNIX and can be configured to receive data from most popular Web browsers.
Tags molecular biology tools & utilities
Updated
September 30 2022
Views
2,265

Molecular biology/Genetics
External Link
COBALT is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and sequence similarity, using RPS-BLAST, BLASTP, and PHI-BLAST.
Tags protein tools & utilities
Updated
September 30 2022
Views
2,247

Molecular biology/Genetics
External Link
Identifies the conserved domains present in a protein sequence. CD-Search uses RPS-BLAST (Reverse Position-Specific BLAST) to compare a query sequence against position-specific score matrices that have been prepared from conserved domain alignments present in the Conserved Domain Database (CDD).
Tags computational biology tools & utilities
Updated
September 30 2022
Views
2,203

Molecular biology/Genetics
External Link
dbVar is NCBI's database of human genomic Structural Variation — large variants >50 bp including insertions, deletions, duplications, inversions, mobile elements, translocations, and complex variants.
Tags dataset genetics genomics tools & utilities
Updated
September 30 2022
Views
2,227

Molecular biology/Genetics
External Link
The database of Genotypes and Phenotypes (dbGaP) was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in Humans.
Tags dataset genetics genomics software tools & utilities
Updated
September 30 2022
Views
2,258

Molecular biology/Genetics
External Link
dbSNP contains human single nucleotide variations, microsatellites, and small-scale insertions and deletions along with publication, population frequency, molecular consequence, and genomic and RefSeq mapping information for both common variations and clinical mutations. dbSNP tutorials can be found at https://github.com/ncbi/dbsnp/tree/master/tutorials
Tags api dataset genetics genomics tools & utilities
Updated
September 30 2022
Views
2,290