Supports finding human phenotype/genotype relationships with queries by phenotype, chromosome location, gene, and SNP identifiers. Currently includes information from dbGaP, the National Human Genome Research Institute (NHGRI) genome-wide association study (GWAS) Catalog, and Genotype - Tissue Expression (GTeX).
A utility for computing alignment of proteins to genomic nucleotide sequence based on a variation of the Needleman Wunsch global alignment algorithm and specifically accounts for introns and splice signals.
A collection of Reference Sequence (RefSeq) proteins, from the complete genomes of prokaryotes, plasmids, and organelles, that have been grouped and annotated based on sequence similarity and protein function.
Information about retroviruses and specialized tools for the analysis of retroviral proteins and genomes. The tools on this page aid in the identification, study and analysis of retroviral genomes and proteins. For instance, the HIV, human interaction database catalogs and organizes published data in peer-reviewed journals regarding HIV-1 and human protein interactions. Several links external to NCBI are also included for the purposes of education, research and health-related matters. These include links to the CDC, the Retroviruses textbook and other informative sites.
An interface for building applications that allows users to combine functions of various NLM drug APIs, including the RxNorm, RxClass, RxTerms, and NDF-RT APIs. Sequences of functions can be executed interactively or in batch mode.
An application for navigating RxNorm drugs. This applications displays relations among drug entities in RxNorm and provides additional information about RxNorm drugs, including drug classes, pill images and drug-drug interactions. RxNav is supported by several drug APIs.
The SKR Project was initiated at NLM in order to develop programs to provide usable semantic representation of biomedical free text by building on resources currently available at the library. The SKR project is concerned with reliable and effective management of the information encoded in natural language texts. The project develops programs that provide usable semantic representation of biomedical text by building on resources currently available at the Library, especially the UMLS knowledge sources and the natural language processing tools provided by the SPECIALIST system. This Java-based API to the Semantic Knowledge Representation (SKR) Scheduler facility was created to provide users with the ability to programmatically submit jobs to the Scheduler Batch and Interactive facilities instead of using the Web-based interface.
The Sequence Read Archive (SRA) stores sequencing data from the next generation of sequencing platforms including Roche 454 GS System®, Illumina Genome Analyzer®, Life Technologies AB SOLiD System®, Helicos Biosciences Heliscope®, Complete Genomics®, and Pacific Biosciences SMRT®.